Injury to or disease of the nervous system can invoke chronic and sometimes intractable
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …

Spreading depolarization (SD) is a phenomenon of various cerebral gray matter structures
that only occurs under pathological conditions. In the present paper, we summarize the …

Focal brain damage after aneurysmal subarachnoid haemorrhage predominantly results
from intracerebral haemorrhage, and early and delayed cerebral ischaemia. The …

We extended the capabilities of functional ultrasound to whole-brain four-dimensional (4D)
neuroimaging. Our multiplane-wave transmission scheme on matrix arrays at thousands of …

Neuronal cytotoxic edema is the morphological correlate of the near-complete neuronal
battery breakdown called spreading depolarization, or conversely, spreading depolarization …

This narrative review provides a broad and comprehensive overview of the most important
discoveries on the postictal state over the past decades as well as recent developments …

Sudden unexpected death in epilepsy (SUDEP) is a fatal complication of epilepsy in which
brainstem spreading depolarization may play a pivotal role, as suggested by animal studies …

Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin
(“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA …

Spreading depolarization is observed as a large negative shift of the direct current potential,
swelling of neuronal somas, and dendritic beading in the brain's gray matter and represents …

Spreading depolarization (SD) occurs frequently in the injured brain, and its neurochemical
effects are detrimental to brain function. We report the first observation that the release of …