Beneficial effects of citrus flavonoids on cardiovascular and metabolic health

AM Mahmoud, RJ Hernandez Bautista… - Oxidative medicine …, 2019 - Wiley Online Library
The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

Flavonoids: Potential candidates for the treatment of neurodegenerative disorders

S Devi, V Kumar, SK Singh, AK Dubey, JJ Kim - Biomedicines, 2021 - mdpi.com
Neurodegenerative disorders, such as Parkinson's disease (PD), Alzheimer's disease (AD),
Amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are the most concerning …

Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases

CG Vazhappilly, SA Ansari, R Al-Jaleeli… - …, 2019 - Springer
The failure of mechanisms of natural anti-coagulation either due to genetic impairment or
due to severe external injuries may result in a condition called thrombosis. This is believed …

Natural drugs as a treatment strategy for cardiovascular disease through the regulation of oxidative stress

X Chang, T Zhang, W Zhang, Z Zhao… - Oxidative Medicine and …, 2020 - Wiley Online Library
Oxidative stress (OS) refers to the physiological imbalance between oxidative and
antioxidative processes leading to increased oxidation, which then results in the …

Pharmacological significance of hesperidin and hesperetin, two citrus flavonoids, as promising antiviral compounds for prophylaxis against and combating COVID-19

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Hesperidin and hesperetin are flavonoids that are abundantly present as constituents of
citrus fruits. These compounds have attracted attention as several computational methods …

Relation of fruits and vegetables with major cardiometabolic risk factors, markers of oxidation, and inflammation

M Lapuente, R Estruch, M Shahbaz, R Casas - Nutrients, 2019 - mdpi.com
Noncommunicable diseases (NCDs) are considered to be the leading cause of death
worldwide. Inadequate fruit and vegetable intake have been recognized as a risk factor for …

Targeting inflammation by flavonoids: novel therapeutic strategy for metabolic disorders

MH Farzaei, AK Singh, R Kumar, CR Croley… - International journal of …, 2019 - mdpi.com
A balanced metabolic profile is essential for normal human physiological activities.
Disproportions in nutrition give rise to imbalances in metabolism that are associated with …

Modulation of Nrf2 by quercetin in doxorubicin-treated rats

A Sharma, M Parikh, H Shah, T Gandhi - Heliyon, 2020 - cell.com
Doxorubicin (DOXO), a potent and widely used chemotherapeutic agent, causes irreversible
heart failure by increasing oxidative stress, which limits its clinical utility. Nuclear factor …

Cocoa, blood pressure, and vascular function

V Ludovici, J Barthelmes, MP Nägele, F Enseleit… - Frontiers in …, 2017 - frontiersin.org
Cardiovascular disease (CVD) represents the most common cause of death worldwide. The
consumption of natural polyphenol-rich foods, and cocoa in particular, has been related to a …

The effect of dietary phytochemicals on nuclear factor erythroid 2-related factor 2 (Nrf2) activation: A systematic review of human intervention trials

T Clifford, JP Acton, SP Cocksedge, KAB Davies… - Molecular biology …, 2021 - Springer
We conducted a systematic review of human trials examining the effects of dietary
phytochemicals on Nrf2 activation. In accordance with the PRISMA guidelines, Medline …