The immunology of Plasmodium vivax malaria

LR Antonelli, C Junqueira, JM Vinetz… - Immunological …, 2020 - Wiley Online Library
Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …

[HTML][HTML] Genetics of malaria inflammatory responses: a pathogenesis perspective

C Penha-Gonçalves - Frontiers in immunology, 2019 - frontiersin.org
Despite significant progress in combating malaria in recent years the burden of severe
disease and death due to Plasmodium infections remains a global public health concern …

[HTML][HTML] Reaching the malaria elimination goal in Brazil: a spatial analysis and time-series study

GZ Laporta, ME Grillet, SR Rodovalho… - Infectious Diseases of …, 2022 - Springer
Abstract Background Since 2015, the Global Technical Strategy (GTS) for Malaria 2016–
2030 has been adopted by the World Health Organization (WHO) as a comprehensive …

[HTML][HTML] HIV infection increases the risk of acquiring Plasmodium vivax malaria: a 4-year cohort study in the Brazilian Amazon HIV and risk of vivax malaria

CVC Guerra, BM da Silva, P Müller… - Scientific Reports, 2022 - nature.com
Globally, malaria and human immunodeficiency virus (HIV) are both independently
associated with a massive burden of disease and death. While their co-infection has been …

[HTML][HTML] Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections

IC Hirako, MM Antunes, RM Rezende… - Scientific Reports, 2022 - nature.com
Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids
and play an important role on host defense. It has been demonstrated that upon infection or …

[HTML][HTML] Association of toll-like receptors in malaria susceptibility and immunopathogenesis: A meta-analysis

ADR Ramirez, MCS de Jesus, J Rossit, NF Reis… - Heliyon, 2022 - cell.com
Toll-like receptors (TLRs) play a key role in the induced immune response in malaria.
Although the potential roles of TLRs have been described, it is necessary to elucidate which …

[HTML][HTML] Evaluation of the malaria elimination policy in Brazil: a systematic review and epidemiological analysis study

JO Melo, MAO Padilha, RTA Barbosa… - Tropical …, 2020 - ncbi.nlm.nih.gov
After a centenary fight against malaria, Brazil has seen an opportunity for change with the
proposal of the malaria elimination policy set by the Brazilian government, in line with …

[PDF][PDF] Toll like receptor-4 gene polymorphism and susceptibility to pulmonary tuberculosis

NA Fouad¹, AM Saeed¹, AW Mahedy - EGYPTIAN JOURNAL OF …, 2019 - bu.edu.eg
Tuberculosis (TB) affects human life globally for a long time. The difference in clinical
outcome of infection suggests that host genetic makeup is responsible for such variability …

[HTML][HTML] Association of Toll-like receptors polymorphisms with the risk of acute lymphoblastic leukemia in the Brazilian Amazon

LA Xabregas, FSA Hanna, F Magalhães-Gama… - Scientific Reports, 2022 - nature.com
Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in
children in childhood. Single-nucleotide polymorphism (SNPs) in key molecules of the …

[HTML][HTML] Polymorphisms in TLRs influence circulating cytokines production in Plasmodium vivax malaria: TLR polymorphisms influence cytokine productions in malaria …

AG Costa, R Ramasawmy, FFA Val, HNS Ibiapina… - Cytokine, 2018 - Elsevier
The efficiency of the immune system has been shaped throughout the evolutionary process
allowing adaptations. In a Plasmodium vivax infection, the host attempts to develop an …