Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

Abstract β-Hydroxybutyrate (βOHB), a ketone body, is oxidised as a brain fuel. Although its
contribution to energy metabolism in the healthy brain is minimal, it is an interesting …

Since it was first generally accepted that the two amino acids glutamate and GABA act as
principal neurotransmitters, several landmark discoveries relating to this function have been …

In today's research environment, children's diet, physical activity, and other lifestyle factors
are commonly studied in the context of health, independent of their effect on cognition and …

Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …

Neurons spurn hydrogen-rich fatty acids for energizing oxidative ATP synthesis, contrary to
other cells. This feature has been mainly attributed to a lower yield of ATP per reduced …

Huntington's disease is a fatal neurodegenerative disease, where dysfunction and loss of
striatal and cortical neurons are central to the pathogenesis of the disease. Here, we …

Brain astrocytes are considered as glycolytic cell type, but these cells also produce ATP via
mitochondrial oxidative phosphorylation. Exposure of cultured primary astrocytes in a …

Ketogenic diets and medium-chain triglycerides are gaining attention as treatment of
neurological disorders. Their major metabolites, β-hydroxybutyrate (βHB) and the medium …

A ketogenic diet (KD) is a normocaloric diet composed by high fat (80–90%), low
carbohydrate, and low protein consumption that induces fasting-like effects. KD increases …