Nowadays, the bacterial drug resistance leads to serious healthy problem worldwide due to
the long-term use and the abuse of traditional antibiotics result in drug resistance of bacteria …

Antimicrobial peptides are an attractive alternative to traditional antibiotics, due to their
physicochemical properties, activity toward a broad spectrum of bacteria, and mode-of …

The use of non-standard toxicity models is a hurdle in the early development of antimicrobial
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …

The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and
periprosthetic joint infection. With the number of primary and revision joint replacement …

Melittin, the main venom component of the European Honeybee, is a cationic linear peptide-
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …

Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …

Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

Antimicrobial peptides (AMPs) have been studied for three decades, and yet a molecular
understanding of their mechanism of action is still lacking. Here we summarize current …

Antimicrobial peptides (AMPs) which predominantly act via membrane active mechanisms
have emerged as an exciting class of antimicrobial agents with tremendous potential to …