Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update

M Omata, AL Cheng, N Kokudo, M Kudo, JM Lee… - Hepatology …, 2017 - Springer
There is great geographical variation in the distribution of hepatocellular carcinoma (HCC),
with the majority of all cases worldwide found in the Asia–Pacific region, where HCC is one …

Comprehensive review of aflatoxin contamination, impact on health and food security, and management strategies in Pakistan

M Ajmal, W Bedale, A Akram, JH Yu - Toxins, 2022 - mdpi.com
Aflatoxins (AFs) are the most important toxic, mutagenic, and carcinogenic fungal toxins that
routinely contaminate food and feed. While more than 20 AFs have been identified to date …

Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects

H Khan, H Ullah, SM Nabavi - Food and Chemical Toxicology, 2019 - Elsevier
The liver is the most essential organ of the body performing vital functions. Hepatic disorders
affect the physiological and biochemical functions of the body. These disorders include …

Role of purinergic receptors in hepatobiliary carcinoma in Pakistani population: an approach towards proinflammatory role of P2X4 and P2X7 receptors

A Asif, M Khalid, S Manzoor, H Ahmad, AU Rehman - Purinergic signalling, 2019 - Springer
The primary malignancy of liver, known as hepatocellular carcinoma (HCC), comprises 9%
of all hepatobiliary carcinomas. A steady rise has also been observed in adenocarcinoma …

[PDF][PDF] Pomegranate peel extract and quercetin possess antioxidant and hepatoprotective activity against concanavalin A-induced liver injury in mice.

S Murtaza, JA Khan, B Aslam, MN Faisal - Pakistan Veterinary Journal, 2021 - pvj.com.pk
Hepatitis is characterized by elevated transaminase enzymes, programmed cell death, and
necrosis that lead to fibrosis and cirrhosis. Excessive immune stimulation plays a pivotal role …

[PDF][PDF] National cancer registry of Pakistan: first comprehensive report of cancer statistics 2015-2019

A Ikram, S Pervez, MT Khadim, M Sohaib… - J Coll Physicians …, 2023 - researchgate.net
Ob ective: o compile a comprehensive national cancer registry report of Pakistan by merging
and analysing cancer registration data received from ma or functional cancer registries in …

[HTML][HTML] Portal vein thrombosis in patients with hepatocellular carcinoma and early cirrhosis—prevalence and risk factors

MTUH Siddiqui, G Fareed, MR Khan, A Riaz… - …, 2023 - ncbi.nlm.nih.gov
Method A retrospective analysis was performed on the prospectively collected data from
January 2018 to March 2020. All patients with HCC discussed in our weekly …

Liver diseases and hepatocellular carcinoma in the Asia-Pacific region: burden, trends, challenges and future directions

LY Mak, K Liu, S Chirapongsathorn, KC Yew… - Nature Reviews …, 2024 - nature.com
Globally, nearly half of deaths from cirrhosis and chronic liver diseases (CLD) and three-
quarters of deaths from hepatocellular carcinoma (HCC) occur in the Asia-Pacific region …

Biomonitoring of Aflatoxin B1 and Deoxynivalenol in a Rural Pakistan Population Using Ultra-Sensitive LC-MS/MS Method

L Xia, MN Routledge, H Rasheed, A Ismail, Y Dong… - Toxins, 2020 - mdpi.com
There are limited data on exposure to mycotoxins in Pakistan. Here, we measured exposure
to deoxynivalenol (DON), a common contaminant of wheat, and aflatoxin B1 (AFB1), a …

[HTML][HTML] Karachi cancer registry (KCR): consolidated data of 5-years 2017-2021.

S Pervez, AA Jabbar, G Haider, MA Qureshi, S Ashraf… - Esophagus, 2023 - jcpsp.pk
Objective: To collect and analyse epidemiologic data of all malignancies by age group and
gender for the Karachi population to estimate the cancer incidence of 5-years (2017-2021) …