Shikonin and its enantiomeric analogue, alkaninn, are prevailing natural lead compounds in
the drug discovery and development of anticancer agents. Despite having numerous …

Gastric cancer remains a significant health burden worldwide. In continuation of our
previous study and development of effective small molecules against gastric cancer, a series …

Cancer is one of the major causes of mortality and morbidity worldwide. Substantial
research efforts have been made to develop new chemical entities with improved anticancer …

A simple and mild protocol for copper-catalyzed oxidation of hydrazones at the α-position
has been reported. Various substrates are compatible, providing the corresponding products …

To identity fast-acting, multistage antimalarial agents, a series of pyridylvinylquinoline-
triazole analogues have been synthesized via CuAAC. Most of the compounds display …

According to the structure‐activity relationships (SAR), we synthesized a series of novel
thiourea derivatives based on the dapsone‐naphthoquinone hybrid by the nucleophilic …

Songorine isolated from Aconitum brachypodum Diels possesses prominent activity of
inhibiting G protein-coupled receptors (GPCRs) in the early screening process. In this paper …

Gynecological malignancy always endangers women's health. Shikonin is a
naphthoquinone compound with a variety of biological activities. Studies have shown that …

The present review explores the critical role of oxime and oxime ether moieties in enhancing
the physicochemical and anticancer properties of structurally diverse molecular frameworks …

In this study, we evaluated the in vitro antitumor activity of dialkylamino-1, 4-
naphthoquinones (1a–n) toward human glioblastoma multiforme cells (GBM02). All the …