Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants

S Wang, Z Yu, C Wang, C Wu, P Guo, J Wei - Molecules, 2018 - mdpi.com
Agarwood, a highly precious non-timber fragrant wood of Aquilaria spp.(Thymelaeaceae),
has been widely used in traditional medicine, religious rites, and cultural activities. Due to …

Medicinal plants with anti-inflammatory activities

F Maione, R Russo, H Khan, N Mascolo - Natural product research, 2016 - Taylor & Francis
Medicinal plants have been the main remedy to treat various ailments for a long time and
nowadays, many drugs have been developed from traditional medicine. This paper reviews …

Molecular insights into the interaction of RONS and Thieno [3, 2-c] pyran analogs with SIRT6/COX-2: A molecular dynamics study

DK Yadav, S Kumar, Saloni, S Misra, L Yadav, M Teli… - Scientific reports, 2018 - nature.com
SIRT6 and COX-2 are oncogenes target that promote the expression of proinflammatory and
pro-survival proteins through a signaling pathway, which leads to increased survival and …

Agarwood oil nanoemulsion attenuates cigarette smoke-induced inflammation and oxidative stress markers in BCi-NS1. 1 airway epithelial cells

G De Rubis, KR Paudel, B Manandhar, SK Singh… - Nutrients, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is an irreversible inflammatory respiratory
disease characterized by frequent exacerbations and symptoms such as cough and …

Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality …

G Aggarwal, M Sharma, R Singh, U Sharma - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance India has an extensive reservoir of traditional wisdom and
a diverse range of medicinal plants that enrich its heritage. Plants have actively been used …

Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay

C Jang, DK Yadav, L Subedi, R Venkatesan… - Scientific reports, 2018 - nature.com
In this study, pharmacophore based 3D QSAR models for human acetylcholinesterase
(AChE) inhibitors were generated, with good significance, statistical values (r2training …

Rediscovering the therapeutic potential of agarwood in the management of chronic inflammatory diseases

JMR Alamil, KR Paudel, Y Chan, D Xenaki… - Molecules, 2022 - mdpi.com
The inflammatory response is a central aspect of the human immune system that acts as a
defense mechanism to protect the body against infections and injuries. A dysregulated …

Computational polypharmacology: a new paradigm for drug discovery

R Chaudhari, Z Tan, B Huang… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Over the past couple of years, the cost of drug development has sharply
increased along with the high rate of clinical trial failures. Such increase in expenses is …

[PDF][PDF] Screening of potent inhibitors against 2019 novel coronavirus (Covid-19) from Allium sativum and Allium cepa: An in silico approach

P Pandey, F Khan, A Kumar… - … Res Appl Chem, 2021 - biointerfaceresearch.com
The infection of the global COVID-19 pandemic and the absence of any possible treatment
options warrants the use of all available resources to find effective drugs against this …

Agarwood essential oil ameliorates restrain stress-induced anxiety and depression by inhibiting HPA axis hyperactivity

S Wang, C Wang, Z Yu, C Wu, D Peng, X Liu… - International journal of …, 2018 - mdpi.com
In our previous investigation, we found that agarwood essential oil (AEO) has a sedative-
hypnotic effect. Sedative-hypnotic drugs usually have an anxiolytic effect, where concomitant …