Group II introns are mobile ribozymes that self-splice from precursor RNAs to yield excised
intron lariat RNAs, which then invade new genomic DNA sites by reverse splicing. The …

Although RNA is generally thought to be a passive genetic blueprint, some RNA molecules,
called ribozymes, have intrinsic enzyme-like activity—they can catalyse chemical reactions …

In nuclear pre-messenger RNA splicing, introns are excised by the spliceosome, a dynamic
machine composed of both proteins and small nuclear RNAs (snRNAs). Over thirty years …

Group II introns are self-splicing ribozymes that catalyze their own excision from precursor
transcripts and insertion into new genetic locations. Here we report the crystal structure of an …

Present in the genomes of bacteria and eukaryotic organelles, group II introns are an
ancient class of ribozymes and retroelements that are believed to have been the ancestors …

Group II introns are remarkable mobile retroelements that use the combined activities of an
autocatalytic RNA and an intron‐encoded reverse transcriptase (RT) to propagate efficiently …

Group II introns are self-splicing ribozymes that share a reaction mechanism and a common
ancestor with the eukaryotic spliceosome, thereby providing a model system for …

It has been nearly 63 years since the first characterization of an RNA triple helix in vitro by
Gary Felsenfeld, David Davies, and Alexander Rich. An RNA triple helix consists of three …

Group II introns are large, autocatalytic ribozymes that catalyze RNA splicing and
retrotransposition. Splicing by group II introns plays a major role in the metabolism of plants …

It is undisputable that the fates of metal ions and nucleic acids are inescapably interwoven.
Metal ions are essential for charge compensation of the negatively charged phosphate …