CD39 and CD73 in immunity and inflammation
The enzymatic activities of CD39 and CD73 play strategic roles in calibrating the duration,
magnitude, and chemical nature of purinergic signals delivered to immune cells through the …
magnitude, and chemical nature of purinergic signals delivered to immune cells through the …
Purinergic signalling in the gastrointestinal tract and related organs in health and disease
G Burnstock - Purinergic signalling, 2014 - Springer
Purinergic signalling plays major roles in the physiology and pathophysiology of digestive
organs. Adenosine 5′-triphosphate (ATP), together with nitric oxide and vasoactive …
organs. Adenosine 5′-triphosphate (ATP), together with nitric oxide and vasoactive …
Molecular signaling and dysfunction of the human reactive enteric glial cell phenotype: implications for GI infection, IBD, POI, neurological, motility, and GI disorders
A Liñán-Rico, F Turco, F Ochoa-Cortes… - Inflammatory bowel …, 2016 - academic.oup.com
Background Clinical observations or animal studies implicate enteric glial cells in motility
disorders, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal (GI) …
disorders, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal (GI) …
Potential for developing purinergic drugs for gastrointestinal diseases
F Ochoa-Cortes, A Liñán-Rico… - Inflammatory bowel …, 2014 - academic.oup.com
Treatments for inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), functional
dyspepsia, or motility disorders are not adequate, and purinergic drugs offer exciting new …
dyspepsia, or motility disorders are not adequate, and purinergic drugs offer exciting new …
The anti-inflammatory effect of resistance training in hypertensive women: the role of purinergic signaling
MD Lammers, NM Aneli, GG de Oliveira… - Journal of …, 2020 - journals.lww.com
Methods: A total of 31 hypertensive group and 28 normotensive (control group) middle-aged
sedentary women were submitted to 6 months of resistance training. All measurements and …
sedentary women were submitted to 6 months of resistance training. All measurements and …
Effect of quercetin on E‐NTPDase/E‐ADA activities and cytokine secretion of complete Freund adjuvant–induced arthritic rats
RSP Saccol, KL da Silveira… - Cell Biochemistry …, 2019 - Wiley Online Library
The effect of quercetin was assessed in rats induced with complete Freund adjuvant (CFA).
Arthritis scores, paw oedema, latency, activities of myeloperoxidase (MPO), ectonucleoside …
Arthritis scores, paw oedema, latency, activities of myeloperoxidase (MPO), ectonucleoside …
Involvement of ectonucleotidases and purinergic receptor expression during acute Chagas disease in the cortex of mice treated with resveratrol and benznidazole
M Fracasso, K Reichert, NB Bottari, AD da Silva… - Purinergic …, 2021 - Springer
Chagas disease (CD) is caused by the parasite Trypanosoma cruzi. CD affects people
worldwide, primarily in tropical areas. The central nervous system (CNS) is an essential site …
worldwide, primarily in tropical areas. The central nervous system (CNS) is an essential site …
High-intensity intermittent exercise increases adenosine hydrolysis in platelets and lymphocytes and promotes platelet aggregation in futsal athletes
VV Miron, J Baldissarelli, G Pranke, A Mânica… - Platelets, 2019 - Taylor & Francis
Acute bouts of high-intensity intermittent exercise (HIIE) or sports are associated with
changes in lymphocytes and platelet functions and we hypothesized that the purinergic …
changes in lymphocytes and platelet functions and we hypothesized that the purinergic …
Swimming training prevents alterations in ecto-NTPDase and adenosine deaminase activities in lymphocytes from Nω-nitro-l-arginine methyl ester hydrochloride …
AM Cardoso, FH Abdalla, MD Bagatini… - Journal of …, 2015 - journals.lww.com
Results: After 6 weeks of training, lymphocytes and serum were separated to be analysed. L-
NAME-treated group displayed an increase in SBP as well as in ecto-NTPDase and …
NAME-treated group displayed an increase in SBP as well as in ecto-NTPDase and …
Defective ATP breakdown activity related to an ENTPD1 gene mutation demonstrated using 31 P NMR spectroscopy
A Nardi-Schreiber, G Sapir, A Gamliel… - Chemical …, 2017 - pubs.rsc.org
The ecto-nucleoside triphosphate diphosphohydrolase-1 (E-NTPDase-1, CD39) enzyme is
responsible for the breakdown of extracellular ATP to ADP and then to AMP by a two-step …
responsible for the breakdown of extracellular ATP to ADP and then to AMP by a two-step …