A review of applications of metabolomics in cancer

RD Beger - Metabolites, 2013 - mdpi.com
Cancer is a devastating disease that alters the metabolism of a cell and the surrounding
milieu. Metabolomics is a growing and powerful technology capable of detecting hundreds …

Metabolomic signature of brain cancer

R Pandey, L Caflisch, A Lodi… - Molecular …, 2017 - Wiley Online Library
Despite advances in surgery and adjuvant therapy, brain tumors represent one of the
leading causes of cancer‐related mortality and morbidity in both adults and children …

The strengths and weaknesses of NMR spectroscopy and mass spectrometry with particular focus on metabolomics research

AHM Emwas - Metabonomics: Methods and protocols, 2015 - Springer
Mass spectrometry (MS) and nuclear magnetic resonance (NMR) have evolved as the most
common techniques in metabolomics studies, and each brings its own advantages and …

Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide

MH Kulke, T O'Dorisio, A Phan… - Endocrine-Related …, 2014 - erc.bioscientifica.com
In this study, we i) assessed the metabolic profile of the normal adrenal cortex and medulla
of adult human subjects by means of 1 H-high-resolution magic-angle spinning nuclear …

Application of NMR metabolomics to search for human disease biomarkers

T Gebregiworgis, R Powers - Combinatorial chemistry & high …, 2012 - ingentaconnect.com
Since antiquity, humans have used body fluids like saliva, urine and sweat for the diagnosis
of diseases. The amount, color and smell of body fluids are still used in many traditional …

HR MAS MR spectroscopy in metabolic characterization of cancer

S Moestue, B Sitter, T Frost Bathen… - Current topics in …, 2011 - ingentaconnect.com
One of the central hallmarks of cancer is the rapid and infinite cellular proliferation. In order
to cope with increased requirement for building blocks and energy, cancer cells develop …

[HTML][HTML] Magnetic resonance spectroscopy for the study of cns malignancies

V Ruiz-Rodado, JR Brender, MK Cherukuri… - Progress in nuclear …, 2021 - Elsevier
Despite intensive research, brain tumors are amongst the malignancies with the worst
prognosis; therefore, a prompt diagnosis and thoughtful assessment of the disease is …

Predicting long‐term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling

MD Cao, B Sitter, TF Bathen, A Bofin… - NMR in …, 2012 - Wiley Online Library
Purpose This study aimed to evaluate whether MR metabolic profiling can be used for
prediction of long‐term survival and monitoring of treatment response in locally advanced …

Analysis of complex mixtures using high-resolution nuclear magnetic resonance spectroscopy and chemometrics

JS McKenzie, JA Donarski, JC Wilson… - Progress in Nuclear …, 2011 - Elsevier
Minor variation in the composition of a mixture can have acute effects on its characteristic
properties, such as flavour, efficacy or toxicity. Thus, the analysis of complex mixtures is of …

Texture analysis of T1‐ and T2‐weighted MR images and use of probabilistic neural network to discriminate posterior fossa tumours in children

E Orphanidou‐Vlachou, N Vlachos… - NMR in …, 2014 - Wiley Online Library
Brain tumours are the most common solid tumours in children, representing 20% of all
cancers. The most frequent posterior fossa tumours are medulloblastomas, pilocytic …