Candida glabrata is a yeast of increasing medical relevance, particularly in critically ill
patients. It is the second most isolated Candida species associated with invasive candidiasis …

Transition metals such as iron, zinc, copper, and manganese are essential for the growth
and development of organisms ranging from bacteria to mammals. Numerous studies have …

Throughout evolution, all organisms have harnessed the redox properties of copper (Cu)
and iron (Fe) as a cofactor or structural determinant of proteins that perform critical functions …

The nature of the cytosolic iron pool remains largely uncharacterized, although a range of
candidate ligands and chaperones have been proposed. Herein an overview is presented of …

Plant pathogens are challenged by host-derived iron starvation or excess during infection,
but the mechanism through which pathogens counteract iron stress is unclear. Here, we …

Poaceae plants can locally accumulate iron to suppress pathogen infection. It remains
unknown how pathogens overcome host-derived iron stress during their successful …

Evidence is reviewed for the role of glutathione in providing a ligand for the cytosolic iron
pool. The possibility of histidine and carnosine forming ternary complexes with iron (II) …

Iron is an essential element for all eukaryote organisms because of its redox properties,
which are important for many biological processes such as DNA synthesis, mitochondrial …

Zinc is an essential nutrient for all forms of life. Within cells, most zinc is bound to protein.
Because zinc serves as a catalytic or structural cofactor for many proteins, cells must …

Zinc homeostasis is essential for fungal growth, as this metal is a critical structural
component of several proteins, including transcription factors. The fungal pathogen …