Clinical applications of carbon nanomaterials in diagnostics and therapy

KP Loh, D Ho, GNC Chiu, DT Leong… - Advanced …, 2018 - Wiley Online Library
Nanomaterials have the potential to improve how patients are clinically treated and
diagnosed. While there are a number of nanomaterials that can be used toward improved …

Nanodiamonds for in vivo applications

KJ Van Der Laan, M Hasani, T Zheng, R Schirhagl - Small, 2018 - Wiley Online Library
Due to their unique optical properties, diamonds are the most valued gemstones. However,
beyond the sparkle, diamonds have a number of unique properties. Their extreme hardness …

Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment

EK Chow, XQ Zhang, M Chen, R Lam… - Science translational …, 2011 - science.org
Enhancing chemotherapeutic efficiency through improved drug delivery would facilitate
treatment of chemoresistant cancers, such as recurrent mammary tumors and liver cancer …

Diamond nanogel-embedded contact lenses mediate lysozyme-dependent therapeutic release

HJ Kim, K Zhang, L Moore, D Ho - ACS nano, 2014 - ACS Publications
Temporarily implanted devices, such as drug-loaded contact lenses, are emerging as the
preferred treatment method for ocular diseases like glaucoma. Localizing the delivery of …

Epirubicin-adsorbed nanodiamonds kill chemoresistant hepatic cancer stem cells

X Wang, XC Low, W Hou, LN Abdullah, TB Toh… - ACS …, 2014 - ACS Publications
Chemoresistance is a primary cause of treatment failure in cancer and a common property of
tumor-initiating cancer stem cells. Overcoming mechanisms of chemoresistance, particularly …

Diamond standard in diagnostics: nanodiamond biolabels make their mark

AS Barnard - Analyst, 2009 - pubs.rsc.org
Fluorescent defects in non-cytotoxic diamond nanoparticles have recently emerged as a
preferred candidate for optical labels in biological and medical imaging. The bright …

Surface charge effects in protein adsorption on nanodiamonds

M Aramesh, O Shimoni, K Ostrikov, S Prawer… - Nanoscale, 2015 - pubs.rsc.org
Understanding the interaction of proteins with charged diamond nanoparticles is of
fundamental importance for diverse biomedical applications. Here we present a thorough …

Atomistic simulation and measurement of pH dependent cancer therapeutic interactions with nanodiamond carrier

A Adnan, R Lam, H Chen, J Lee… - Molecular …, 2011 - ACS Publications
In this work, we have combined constant-pH molecular dynamics simulations and
experiments to provide a quantitative analysis of pH dependent interactions between …

Nanodiamond–mitoxantrone complexes enhance drug retention in chemoresistant breast cancer cells

TB Toh, DK Lee, W Hou, LN Abdullah… - Molecular …, 2014 - ACS Publications
Chemoresistance is a prevalent issue that accounts for the vast majority of treatment failure
outcomes in metastatic cancer. Among the mechanisms of resistance that markedly …

RSM models approach for optimization of the mechanical properties of electroless Ni-B-nanodiamond coating: An experimental and molecular dynamic simulation …

S Yazdani, V Vitry - Surface and Coatings Technology, 2023 - Elsevier
This report explores the effects of electroless Ni-B-nanodiamond plating bath parameters for
optimization of the hardness and deposition rate based on response surface method (RSM) …