Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
Unlocking the power of exosomes for crossing biological barriers in drug delivery
RO Elliott, M He - Pharmaceutics, 2021 - mdpi.com
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …
of nanovesicles called exosomes has been driving the research field to a new regime for …
Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
Exosomes and other extracellular vesicles in host–pathogen interactions
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …
Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies
M Record, K Carayon, M Poirot… - Biochimica et Biophysica …, 2014 - Elsevier
Exosomes are nanovesicles that have emerged as a new intercellular communication
system between an intracellular compartment of a donor cell towards the periphery or an …
system between an intracellular compartment of a donor cell towards the periphery or an …
Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials
AV Vlassov, S Magdaleno, R Setterquist… - Biochimica et Biophysica …, 2012 - Elsevier
BACKGROUND: Cells continuously secrete a large number of microvesicles,
macromolecular complexes, and small molecules into the extracellular space. Of the …
macromolecular complexes, and small molecules into the extracellular space. Of the …
Extracellular vesicles: lipids as key components of their biogenesis and functions
M Record, S Silvente-Poirot, M Poirot… - Journal of lipid …, 2018 - ASBMB
Intercellular communication has been known for decades to involve either direct contact
between cells or to operate via circulating molecules, such as cytokines, growth factors, or …
between cells or to operate via circulating molecules, such as cytokines, growth factors, or …
hucMSC derived exosomes promote functional recovery in spinal cord injury mice via attenuating inflammation
G Sun, G Li, D Li, W Huang, R Zhang, H Zhang… - Materials Science and …, 2018 - Elsevier
The exploration of effective spinal cord injury (SCI) healing still remain a great challenge
due to the high morbidity, complex pathology and unclear targets. Human umbilical cord …
due to the high morbidity, complex pathology and unclear targets. Human umbilical cord …
Membrane vesicles as conveyors of immune responses
C Théry, M Ostrowski, E Segura - Nature reviews immunology, 2009 - nature.com
In multicellular organisms, communication between cells mainly involves the secretion of
proteins that then bind to receptors on neighbouring cells. But another mode of intercellular …
proteins that then bind to receptors on neighbouring cells. But another mode of intercellular …
Dexosomes as a cell-free vaccine for cancer immunotherapy
Dendritic cells (DCs) secrete vast quantities of exosomes termed as dexosomes.
Dexosomes are symmetric nanoscale heat-stable vesicles that consist of a lipid bilayer …
Dexosomes are symmetric nanoscale heat-stable vesicles that consist of a lipid bilayer …