Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

A review of aptamer-based SERS biosensors: Design strategies and applications

M Muhammad, Q Huang - Talanta, 2021 - Elsevier
Surface-enhanced Raman spectroscopy, due to its high sensitivity, unique vibrational
fingerprint identification of molecules and easy operation, has been extensively applied in …

Structural biology for the molecular insight between aptamers and target proteins

N Zhang, Z Chen, D Liu, H Jiang, ZK Zhang… - International Journal of …, 2021 - mdpi.com
Aptamers are promising therapeutic and diagnostic agents for various diseases due to their
high affinity and specificity against target proteins. Structural determination in combination …

Blood plasma surface-enhanced Raman spectroscopy for non-invasive optical detection of cervical cancer

S Feng, D Lin, J Lin, B Li, Z Huang, G Chen, W Zhang… - Analyst, 2013 - pubs.rsc.org
Based on blood plasma surface-enhanced Raman spectroscopy (SERS) analysis, a simple
and label-free blood test for non-invasive cervical cancer detection is presented in this …

Detection of adenosine triphosphate with an aptamer biosensor based on surface-enhanced Raman scattering

M Li, J Zhang, S Suri, LJ Sooter, D Ma… - Analytical chemistry, 2012 - ACS Publications
A simple, ultrasensitive, highly selective, and reagent-free aptamer-based biosensor has
been developed for quantitative detection of adenosine triphosphate (ATP) using surface …

Molecular affinity agents for intrinsic surface-enhanced Raman scattering (SERS) sensors

VM Szlag, RS Rodriguez, J He… - … applied materials & …, 2018 - ACS Publications
Research at the interface of synthetic materials, biochemistry, and analytical techniques has
enabled sensing platforms for applications across many research communities. Herein we …

G-quadruplex DNA aptamers and their ligands: structure, function and application

WO Tucker, KT Shum… - Current pharmaceutical …, 2012 - ingentaconnect.com
Highly specific and tight-binding nucleic acid aptamers have been selected against a variety
of molecular targets for over 20 years. A significant proportion of these oligonucleotides …

Surface-enhanced Raman spectroscopy of saliva proteins for the noninvasive differentiation of benign and malignant breast tumors

S Feng, S Huang, D Lin, G Chen, Y Xu… - International journal …, 2015 - Taylor & Francis
The capability of saliva protein analysis, based on membrane protein purification and
surface-enhanced Raman spectroscopy (SERS), for detecting benign and malignant breast …

SERS-based detection of biomolecules

D Cialla, S Pollok, C Steinbrücker, K Weber, J Popp - Nanophotonics, 2014 - degruyter.com
In order to detect biomolecules, different approaches using for instance biological,
spectroscopic or imaging techniques are established. Due to the broad variety of these …

Targeting gold nanoshells on silica nanorattles: a drug cocktail to fight breast tumors via a single irradiation with near‐infrared laser light

H Liu, T Liu, X Wu, L Li, L Tan, D Chen, F Tang - Advanced Materials, 2012 - infona.pl
The drug‐loaded, transferrin and poly (ethylene glycol)(PEG)‐functionalized gold
nanoshells on silica nanorattles (pGSNs‐Doc‐Tf) can combine the active targeting, passive …