Microbiota in pancreatic health and disease: the next frontier in microbiome research

RM Thomas, C Jobin - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
Diseases intrinsic to the pancreas such as pancreatitis, pancreatic cancer and type 1
diabetes mellitus impart substantial health and financial burdens on society but identification …

Critical thresholds: key to unlocking the door to the prevention and specific treatments for acute pancreatitis

SG Barreto, A Habtezion, A Gukovskaya, A Lugea… - Gut, 2021 - gut.bmj.com
Acute pancreatitis (AP), an acute inflammatory disorder of the exocrine pancreas, is one of
the most common gastrointestinal diseases encountered in emergency departments with no …

Assessment of the course of acute pancreatitis in the light of aetiology: a systematic review and meta-analysis

ER Bálint, G Fűr, L Kiss, DI Németh, A Soós, P Hegyi… - Scientific Reports, 2020 - nature.com
The main causes of acute pancreatitis (AP) are biliary disease, alcohol consumption,
hypertriglyceridaemia (HTG) and endoscopic retrograde cholangiopancreatography …

Российский консенсус по диагностике и лечению хронического панкреатита

ИЕ Хатьков, ИВ Маев, СР Абдулхаков… - Терапевтический …, 2017 - cyberleninka.ru
Российский консенсус (согласительный документ) по диагностике и лечению
хронического панкреатита подготовлен по инициативе Российского « …

Trends and recent developments in pharmacotherapy of acute pancreatitis

J Hey-Hadavi, P Velisetty, S Mhatre - Postgraduate Medicine, 2023 - Taylor & Francis
Acute pancreatitis (AP), a complex inflammatory disease of the pancreas, is associated with
increased morbidity and mortality. Currently, no specific therapies are approved for its …

[HTML][HTML] Uniting epidemiology and experimental disease models for alcohol-related pancreatic disease

VW Setiawan, K Monroe, A Lugea… - Alcohol research …, 2017 - ncbi.nlm.nih.gov
Findings from epidemiologic studies and research with experimental animal models provide
insights into alcohol-related disease pathogeneses. Epidemiologic data indicate that heavy …

TH1 and TH2 cytokine profiles as predictors of severity in acute pancreatitis

A Rodriguez-Nicolas, A Martínez-Chamorro… - Pancreas, 2018 - journals.lww.com
Objectives Acute pancreatitis (AP) is severe in up to 20% of patients, with a high mortality
rate. Quantification of serum TH1 and TH2 cytokines may provide objective evidence to …

Chymotrypsinogen C genetic variants, including c. 180TT, are strongly associated with chronic pancreatitis in pediatric patients

AM Grabarczyk, G Oracz… - Journal of pediatric …, 2017 - journals.lww.com
Objectives: Genetic studies in adults/adolescent patients with chronic pancreatitis (CP)
identified chymotrypsinogen C (CTRC) genetic variants but their association with CP risk …

Genetic Factors in Acute Pancreatitis

ML Ramsey, GI Papachristou - The Pancreas: An Integrated …, 2023 - Wiley Online Library
While many cases of acute pancreatitis (AP) among adults are attributed to gallstones and
alcohol, the majority of people with these risk factors never develop AP. It is increasingly …

Risk of chronic pancreatitis in carriers of loss-of-function CTRC variants: A meta-analysis

A Takáts, G Berke, N Gede, BC Németh, H Witt… - Plos one, 2022 - journals.plos.org
The digestive protease chymotrypsin C (CTRC) protects the pancreas against pancreatitis
by degrading potentially harmful trypsinogen. Loss-of-function genetic variants in CTRC …