[HTML][HTML] Liver immunology
The liver is the largest organ in the body and is generally regarded by non-immunologists as
not having lymphoid function. However, such is far from accurate. This review highlights the …
not having lymphoid function. However, such is far from accurate. This review highlights the …
Protective immunity against hepatitis C: many shades of gray
MS Abdel-Hakeem, NH Shoukry - Frontiers in immunology, 2014 - frontiersin.org
The majority of individuals who become acutely infected with hepatitis C virus (HCV)
develop chronic infection and suffer from progressive liver damage while approximately …
develop chronic infection and suffer from progressive liver damage while approximately …
Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease
Tissue fibrosis is a core pathologic process that contributes to mortality in~ 45% of the
population and is likely to be influenced by the host genetic architecture. Here we …
population and is likely to be influenced by the host genetic architecture. Here we …
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
BACKGROUND & AIMS: Polymorphisms in IL28B were shown to affect clearance of
hepatitis C virus (HCV) infection in genome-wide association (GWA) studies. Only a fraction …
hepatitis C virus (HCV) infection in genome-wide association (GWA) studies. Only a fraction …
[HTML][HTML] Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention
A distinctive type of (uterine) natural killer (NK) cell is present in the uterine decidua during
the period of placental formation. Uterine NK cells express members of the killer …
the period of placental formation. Uterine NK cells express members of the killer …
[PDF][PDF] Hepatitis C virus transmission among human immunodeficiency virus‐infected men who have sex with men: modeling the effect of behavioral and treatment …
L Salazar‐Vizcaya, RD Kouyos, C Zahnd… - …, 2016 - Wiley Online Library
The incidence of hepatitis C virus (HCV) infections among human immunodeficiency virus
(HIV)‐infected men who have sex with men has increased in recent years and is associated …
(HIV)‐infected men who have sex with men has increased in recent years and is associated …
Immunogenomics of killer cell immunoglobulin-like receptor (KIR) and HLA class I: coevolution and consequences for human health
NR Pollock, GF Harrison, PJ Norman - The Journal of Allergy and Clinical …, 2022 - Elsevier
Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …
Genetics of IL28B and HCV—response to infection and treatment
CN Hayes, M Imamura, H Aikata… - Nature reviews …, 2012 - nature.com
The IL28B locus attracted the attention of HCV researchers after a series of genome-wide
association studies independently identified a strong association between common IL28B …
association studies independently identified a strong association between common IL28B …
IRAKM‐Mincle axis links cell death to inflammation: pathophysiological implications for chronic alcoholic liver disease
CTNNB1 mutations activating ß‐catenin are frequent somatic events in hepatocellular
carcinoma (HCC) and adenoma (HCA), particularly associated with a risk of malignant …
carcinoma (HCC) and adenoma (HCA), particularly associated with a risk of malignant …
Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C
MA Jiménez-Sousa, A Fernández-Rodríguez… - BMC medicine, 2013 - Springer
Background Since 2009, several studies have identified single-nucleotide polymorphisms
(SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated …
(SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated …