[HTML][HTML] The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review
J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …
[HTML][HTML] Fisetin, a potent anticancer flavonol exhibiting cytotoxic activity against neoplastic malignant cells and cancerous conditions: a scoping, comprehensive …
Diet plays a crucial role in homeostasis maintenance. Plants and spices containing
flavonoids have been widely used in traditional medicine for thousands of years. Flavonols …
flavonoids have been widely used in traditional medicine for thousands of years. Flavonols …
[HTML][HTML] The impact of oxidative stress and AKT pathway on cancer cell functions and its application to natural products
Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …
several cell functions of cancer cells. Several natural products modulate both oxidative …
[HTML][HTML] Targeting cancer stem cells by dietary agents: an important therapeutic strategy against human malignancies
M Deldar Abad Paskeh, S Asadi, A Zabolian… - International Journal of …, 2021 - mdpi.com
As a multifactorial disease, treatment of cancer depends on understanding unique
mechanisms involved in its progression. The cancer stem cells (CSCs) are responsible for …
mechanisms involved in its progression. The cancer stem cells (CSCs) are responsible for …
[HTML][HTML] Selected flavonols in breast and gynecological cancer: a systematic review
D Wendlocha, K Krzykawski, A Mielczarek-Palacz… - Nutrients, 2023 - mdpi.com
The consumption of foods that are rich in phenolic compounds has chemopreventive effects
on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide …
on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide …
[HTML][HTML] Fisetin—In search of better bioavailability—From macro to nano modifications: A review
J Szymczak, J Cielecka-Piontek - International Journal of Molecular …, 2023 - mdpi.com
As secondary plant metabolites, polyphenols are abundant in fruits and vegetables. They
are in high demand because of their many health benefits. However, their low bioavailability …
are in high demand because of their many health benefits. However, their low bioavailability …
[HTML][HTML] Molecular Mechanisms of Flavonoids against Tumor Gamma-Herpesviruses and Their Correlated Cancers—A Focus on EBV and KSHV Life Cycles and …
STS Hassan, M Šudomová - International Journal of Molecular Sciences, 2022 - mdpi.com
Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are cancer-
causing viruses that belong to human gamma-herpesviruses. They are DNA viruses known …
causing viruses that belong to human gamma-herpesviruses. They are DNA viruses known …
Phytochemicals for the prevention and treatment of pancreatic cancer: Current progress and future prospects
N Casarcia, P Rogers, E Guld, S Iyer… - British Journal of …, 2023 - Wiley Online Library
Pancreatic cancer is the third leading cause of cancer‐related deaths in the United States,
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …
Fisetin-loaded grape-derived nanoparticles improve anticancer efficacy in MOLT-4 cells
P Sarvarian, P Samadi, E Gholipour… - Biochemical and …, 2023 - Elsevier
Purpose Fisetin (FIS) is a natural flavonoid with anti-proliferative and anti-apoptotic effects
on different human cancer cell lines and can be considered a therapeutic agent for ALL …
on different human cancer cell lines and can be considered a therapeutic agent for ALL …
[HTML][HTML] Autophagy as a therapeutic target of natural products enhancing embryo implantation
Infertility is an emerging health issue worldwide, and female infertility is intimately
associated with embryo implantation failure. Embryo implantation is an essential process …
associated with embryo implantation failure. Embryo implantation is an essential process …