Health benefits of fraxetin: from chemistry to medicine

NM Ha, NT Son - Archiv der Pharmazie, 2024 - Wiley Online Library
Fraxetin is a bioactive molecule present in various natural plants, especially Cortex Fraxini.
Evidenced outcomes in phytochemical and biological analyses for this agent are now …

A review of natural products targeting tumor immune microenvironments for the treatment of lung cancer

P Yao, S Liang, Z Liu, C Xu - Frontiers in Immunology, 2024 - frontiersin.org
Lung cancer (LC) produces some of the most malignant tumors in the world, with high
morbidity and mortality. Tumor immune microenvironment (TIME), a component of the tumor …

Oxymatrine Improves Oxidative Stress-Induced Senescence in HT22 Cells and Mice via the Activation of AMP-Activated Protein Kinase

N Maharajan, CM Lee, KA Vijayakumar, GW Cho - Antioxidants, 2023 - mdpi.com
The accumulation of oxidative stress is one of the important factors causing cellular
senescence. Oxymatrine (OM) is a natural quinolizidine alkaloid compound known for its …

Scutellarein: a review of chemistry and pharmacology

NT Thoa, NT Son - Journal of Pharmacy and Pharmacology, 2024 - academic.oup.com
Objectives To get a better understanding of the scientific values of flavone scutellarein
(SCT), and to encourage its applications in human health, the current review systematically …

Exploring the potential role of genus Sophora in the management of osteoporosis: a phytochemical and biological review

SH Aly, AMM Elbadry, M El-Shazly… - Frontiers in Natural …, 2023 - frontiersin.org
Bone metabolism is characterized by an interplay between the deposition of bone matrix
and mineralization and the resorption process. Osteoporosis is a form of systemic metabolic …

Traditional Chinese medicine treats ulcerative colitis by regulating gut microbiota, signaling pathway and cytokine: Future novel method option for pharmacotherapy

T Wang, X Liu, W Zhang, J Wang, T Wang, W Yue… - Heliyon, 2024 - cell.com
Background Ulcerative colitis (UC) is a chronic non-specific inflammatory disease with
intestinal tract as the main site. The pathogenic of UC has not yet been clarified, and multiple …

Oxymatrine combined with rapamycin to attenuate acute cardiac allograft rejection

X Lan, J Zhang, S Ren, H Wang, B Shao, Y Qin, H Qin… - Heliyon, 2024 - cell.com
Background and aim Solid organ transplantation remains a life-saving therapeutic option for
patients with end-stage organ dysfunction. Acute cellular rejection (ACR), dominated by …

Oxymatrine Alleviates High-Fat-High-Fructose-Induced Fatty Liver in Rats: Understanding the Molecular Mechanism Through an Untargeted Metabonomics Study

H Li, C Wang, Q Wang, X Liu, J Zhang… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Objective Previous studies have shown that oxymatrine (OMT) can improve high-fat-high-
fructose-diet-induced non-alcoholic fatty liver disease (NAFLD), and our study aimed to …

A Comprehensive Review on the Effect of Natural Products on Colorectal Cancer

VA Afrose Farzana, S Kumaran… - Current Pharmacology …, 2024 - Springer
Abstract Purpose of Review This article provides insight and information on selected natural
products against colorectal cancer and its mechanism of action. Recent Findings Colorectal …

Pristimerin: Natural Occurrence, Biosynthesis, Pharmacology, and Pharmacokinetics

DTL Huong, NT Son - Revista Brasileira de Farmacognosia, 2024 - Springer
Pristimerin is a naturally occurring triterpenoid originally isolated from plant members of the
genus Pristimera Miers, Celastraceae, and can be also isolated from the species of the …