[HTML][HTML] Indole-3-carbinol and prostate cancer
FH Sarkar, Y Li - The Journal of nutrition, 2004 - Elsevier
Epidemiological and dietary studies have revealed an association between high dietary
intake of cruciferous vegetables and decreased prostate cancer risk. Our studies have …
intake of cruciferous vegetables and decreased prostate cancer risk. Our studies have …
[HTML][HTML] Role of retinoids in the prevention and treatment of colorectal cancer
CC Applegate, MA Lane - World journal of gastrointestinal …, 2015 - ncbi.nlm.nih.gov
Vitamin A and its derivatives, retinoids, have been widely studied for their use as cancer
chemotherapeutic agents. With respect to colorectal cancer (CRC), several critical mutations …
chemotherapeutic agents. With respect to colorectal cancer (CRC), several critical mutations …
Indole-3-carbinol suppresses NF-κB and IκBα kinase activation, causing inhibition of expression of NF-κB-regulated antiapoptotic and metastatic gene products and …
Y Takada, M Andreeff, BB Aggarwal - Blood, 2005 - ashpublications.org
Abstract Indole-3-carbinol, found in Brassica species vegetables (such as cabbage,
cauliflower, and brussels spouts), exhibits antitumor effects through poorly defined …
cauliflower, and brussels spouts), exhibits antitumor effects through poorly defined …
Cellular and molecular determinants of all‐trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression
F Centritto, G Paroni, M Bolis, SK Garattini… - EMBO molecular …, 2015 - embopress.org
Forty‐two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all‐
trans retinoic acid (ATRA) sensitivity. Luminal and ER+(estrogen‐receptor‐positive) cell …
trans retinoic acid (ATRA) sensitivity. Luminal and ER+(estrogen‐receptor‐positive) cell …
Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets
M Terao, M Fratelli, M Kurosaki, A Zanetti… - Journal of Biological …, 2011 - ASBMB
Retinoids are promising agents for the treatment/prevention of breast carcinoma. We
examined the role of microRNAs in mediating the effects of all-trans-retinoic acid (ATRA) …
examined the role of microRNAs in mediating the effects of all-trans-retinoic acid (ATRA) …
Retinoic acid represses invasion and stem cell phenotype by induction of the metastasis suppressors RARRES1 and LXN
EE Oldridge, HF Walker, MJ Stower, MS Simms… - Oncogenesis, 2013 - nature.com
The mouse haematopoietic stem cell (SC) regulator Latexin (LXN) is the only known
homologue of the retinoic acid receptor responder 1 (RARRES1) gene. Both genes lie …
homologue of the retinoic acid receptor responder 1 (RARRES1) gene. Both genes lie …
Indole-3-carbinol Inhibits 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Plus Benzo(a)pyrene–Induced Lung Tumorigenesis in A/J Mice and Modulates Carcinogen …
F Kassie, LB Anderson, R Scherber, N Yu, D Lahti… - Cancer Research, 2007 - AACR
We tested the chemopreventive efficacy of indole-3-carbinol (I3C), a constituent of Brassica
vegetables, and its major condensation product, 3, 3′-diindolylmethane (DIM), against lung …
vegetables, and its major condensation product, 3, 3′-diindolylmethane (DIM), against lung …
Plant polyphenolics as anti-invasive cancer agents
VS Parmar, ME Bracke… - Anti-Cancer Agents …, 2008 - ingentaconnect.com
Because invasion is, either directly or via metastasis formation, the main cause of death in
cancer patients, development of efficient anti-invasive agents is an important research …
cancer patients, development of efficient anti-invasive agents is an important research …
Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: potent cytotoxicity of resveratrol to normal cells
A Fujimoto, Y Sakanashi, H Matsui… - Basic & Clinical …, 2009 - Wiley Online Library
The chemopreventive and chemotherapeutic actions of polyphenols and related phenolics
have received considerable attention since these compounds induce apoptosis in several …
have received considerable attention since these compounds induce apoptosis in several …
Retinol Inhibits the Invasion of Retinoic Acid–Resistant Colon Cancer Cells In Vitro and Decreases Matrix Metalloproteinase MRNA, Protein, and Activity Levels
EY Park, ET Wilder, MA Lane - Nutrition and cancer, 2007 - Taylor & Francis
Retinol inhibits the growth of all-trans-retinoic acid (ATRA)-resistant human colon cancer cell
lines through a retinoic acid receptor (RAR)-independent mechanism. The objectives of the …
lines through a retinoic acid receptor (RAR)-independent mechanism. The objectives of the …