Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

Abstract tRNAs, nexus molecules between mRNAs and proteins, have a central role in
translation. Recent discoveries have revealed unprecedented complexity of tRNA …

An extensive repertoire of modifications is known to underlie the versatile coding, structural
and catalytic functions of RNA, but it remains largely uncharted territory. Although …

MODOMICS is a database of RNA modifications that provides comprehensive information
concerning the chemical structures of modified ribonucleosides, their biosynthetic pathways …

Abstract N 6-methyladenosine–sequencing (m6A-seq) is an immunocapturing approach for
the unbiased transcriptome-wide localization of m6A in high resolution. To our knowledge …

Since its inception in 1994, The RNA Modification Database (RNAMDB, http://rna-mdb. cas.
albany. edu/RNAmods/) has served as a focal point for information pertaining to naturally …

Abstract N6-methyl-adenosine (m6A) is one of the most common and abundant
modifications on RNA molecules present in eukaryotes. However, the biological significance …

Posttranscriptional modifications of transfer RNAs (tRNAs) are critical for all core aspects of
tRNA function, such as folding, stability, and decoding. Most tRNA modifications were …

Mitochondria are eukaryotic organelles that generate most of the energy in the cell by
oxidative phosphorylation (OXPHOS). Each mitochondrion contains multiple copies of a …

Abstract The BRENDA (BRaunschweig ENzyme DAtabase) enzyme portal (http://www.
brenda-enzymes. org) is the main information system of functional biochemical and …