Exploring the efficacy of natural products in alleviating Alzheimer's disease
Alzheimer's disease (hereafter AD) is a progressive neurodegenerative disorder that affects
the central nervous system. There are multiple factors that cause AD, viz., accumulation of …
the central nervous system. There are multiple factors that cause AD, viz., accumulation of …
Building an ommatidium one cell at a time
JP Kumar - Developmental Dynamics, 2012 - Wiley Online Library
Since the discovery of a single white‐eyed male in a population of red eyed flies over 100
years ago (Morgan, 1910), the compound eye of the fruit fly, Drosophila melanogaster, has …
years ago (Morgan, 1910), the compound eye of the fruit fly, Drosophila melanogaster, has …
[HTML][HTML] A survey of 6,300 genomic fragments for cis-regulatory activity in the imaginal discs of Drosophila melanogaster
Over 6,000 fragments from the genome of Drosophila melanogaster were analyzed for their
ability to drive expression of GAL4 reporter genes in the third-instar larval imaginal discs …
ability to drive expression of GAL4 reporter genes in the third-instar larval imaginal discs …
Buffering and amplifying transcriptional noise during cell fate specification
EA Urban, RJ Johnston Jr - Frontiers in genetics, 2018 - frontiersin.org
The molecular processes that drive gene transcription are inherently noisy. This noise often
manifests in the form of transcriptional bursts, producing fluctuations in gene activity over …
manifests in the form of transcriptional bursts, producing fluctuations in gene activity over …
A positive feedback loop of Hippo-and c-Jun-amino-terminal kinase signaling pathways regulates amyloid-beta-mediated neurodegeneration
Alzheimer's disease (AD, OMIM: 104300) is an age-related disorder that affects millions of
people. One of the underlying causes of AD is generation of hydrophobic amyloid-beta 42 …
people. One of the underlying causes of AD is generation of hydrophobic amyloid-beta 42 …
A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye
Abstract Alzheimer's disease (AD), a fatal progressive neurodegenerative disorder, also
results from accumulation of amyloid-beta 42 (Aβ42) plaques. These Aβ42 plaques trigger …
results from accumulation of amyloid-beta 42 (Aβ42) plaques. These Aβ42 plaques trigger …
[HTML][HTML] Master regulators in development: Views from the Drosophila retinal determination and mammalian pluripotency gene networks
TL Davis, I Rebay - Developmental biology, 2017 - Elsevier
Among the mechanisms that steer cells to their correct fate during development, master
regulatory networks are unique in their sufficiency to trigger a developmental program …
regulatory networks are unique in their sufficiency to trigger a developmental program …
Sox9+ messenger cells orchestrate large-scale skeletal regeneration in the mammalian rib
ST Kuwahara, MA Serowoky, V Vakhshori… - Elife, 2019 - elifesciences.org
Most bones in mammals display a limited capacity for natural large-scale repair. The ribs are
a notable exception, yet the source of their remarkable regenerative ability remains …
a notable exception, yet the source of their remarkable regenerative ability remains …
The fly eye: Through the looking glass
JP Kumar - Developmental dynamics, 2018 - Wiley Online Library
The developing eye‐antennal disc of Drosophila melanogaster has been studied for more
than a century, and it has been used as a model system to study diverse processes, such as …
than a century, and it has been used as a model system to study diverse processes, such as …
Alzheimer's disease: the silver tsunami of the 21: st: century
Abstract Alzheimer's disease (AD), a fatal progressive neurodegenerative disorder, has no
cure to date. One of the causes of AD is the accumulation of amyloid-beta 42 (Aβ42) …
cure to date. One of the causes of AD is the accumulation of amyloid-beta 42 (Aβ42) …