Sodium-coupled neurotransmitter transporters play a fundamental role in the termination of
synaptic neurotransmission, which makes them a major drug target. The reconstitution of …

CLCs are dimeric membrane chloride channels and anion/proton exchangers regulating
processes such as muscle contraction and endo-lysosome acidification. Their activity is …

Glutamate is the main excitatory transmitter in the mammalian central nervous system;
glutamate transporters keep the synaptic glutamate concentrations at bay for normal brain …

Membrane transporter proteins play critical roles in understanding biological processes,
disease mechanisms, and drug development. One unique type of membrane transporter is …

The CLC family of membrane proteins are a widespread group of membraneproteins, found
in both prokaryotes and eukaryotes. This family includes two differentfunctional members; …