Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria

R Maddamsetti, Y Yao, T Wang, J Gao… - Nature …, 2024 - nature.com
Horizontal gene transfer (HGT) and gene duplication are often considered as separate
mechanisms driving the evolution of new functions. However, the mobile genetic elements …

Genetic Configuration of Genomic Resistance Islands in Acinetobacter baumannii Clinical Isolates From Egypt

SM Hamed, AFA Hussein, MH Al-Agamy… - Frontiers in …, 2022 - frontiersin.org
In Acinetobacter baumannii (A. baumannii), a wide repertoire of resistance genes is often
carried within genomic resistance islands (RIs), particularly in high-risk global clones (GCs) …

Manipulation of natural transformation by AbaR-type islands promotes fixation of antibiotic resistance in Acinetobacter baumannii

R Tuffet, G Carvalho, AS Godeux… - Proceedings of the …, 2024 - pnas.org
The opportunistic pathogen Acinetobacter baumannii, carries variants of A. baumannii
resistance islands (AbaR)-type genomic islands conferring multidrug resistance. Their …

Dissemination of the Acinetobacter baumannii isolates belonging to global clone 2 containing AbGRI resistance islands in a referral hospital

G Naderi, M Asadian, A Seifi, S Ghourchian… - Microbiology …, 2023 - Am Soc Microbiol
Acinetobacter baumannii strains belonging to global clone 2 (GC2) contain resistance
islands (AbGRIs), which are composed of genes conferring resistance to older and newer …

Emergence and Evolution of OXA-23-Producing ST46Pas-ST462Oxf-KL28-OCL1 Carbapenem-Resistant Acinetobacter baumannii Mediated by a Novel IS Aba1 …

H Liu, X Liu, J He, L Zhang, F Zhao, Z Zhou, X Hua… - Antibiotics, 2023 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) isolates of global clone 1 (GC1)
and global clone 2 (GC2) have been widely reported. Nevertheless, non-GC1 and non-GC2 …

Occurrence of Acinetobacter baumannii genomic resistance islands (AbGRIs) in Acinetobacter baumannii strains belonging to global clone 2 obtained from COVID …

G Naderi, M Asadian, PA Khaki, M Salehi, A Abdollahi… - BMC microbiology, 2023 - Springer
Abstract Aim The Acinetobacter baumannii genomic resistance islands (AbGRIs), which
were characterized in the genome of the global clone 2 (GC2) A. baumannii contain …

Hackflex library preparation enables low-cost metagenomic profiling

SL Goldman, JG Sanders, DD Sprockett… - ISME …, 2024 - academic.oup.com
Shotgun metagenomic sequencing provides valuable insights into microbial communities,
but the high cost of library preparation with standard kits and protocols is a barrier for many …