Secondary metabolite biosynthesis genes in fungi are usually physically linked and
organized in large gene clusters. The physical linkage of genes involved in the same …

The cereal pathogen Fusarium graminearum produces secondary metabolites toxic to
humans and animals, yet coordinated transcriptional regulation of gene clusters remains …

Mycotoxins are natural contaminants of food and feed products, posing a substantial health
risk to humans and animals throughout the world. A plethora of filamentous fungi has been …

The microbial world offers a rich source of bioactive compounds for those able to sift through
it. Technologies capable of quantitatively detecting natural products while simultaneously …

Regulation of secondary metabolite (SM) gene clusters in A spergillus nidulans has been
shown to occur through cluster‐specific transcription factors or through global regulators of …

Secondary metabolism and development are linked in Aspergillus through the conserved
regulatory velvet complex composed of VeA, VelB, and LaeA. The founding member of the …

ABSTRACT G protein-coupled receptors (GPCRs) are transmembrane receptors that relay
signals from the external environment inside the cell, allowing an organism to adapt to its …

Histone deacetylases (HDACs) always function as corepressors and sometimes as
coactivators in the regulation of fungal development and secondary metabolite production …

The filamentous fungi in the genus Aspergillus are opportunistic plant and animal pathogens
that can adapt to their environment by producing various secondary metabolites, including …

Penicillium marneffei is an opportunistic pathogen of humans and displays a temperature
dependent dimorphic transition. Like many fungi, exogenous DNA introduced by DNA …