Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification
Establishment of a functional vascular network is rate-limiting in embryonic development,
tissue repair and engineering. During blood vessel formation, newly generated endothelial …
tissue repair and engineering. During blood vessel formation, newly generated endothelial …
iProEP: a computational predictor for predicting promoter
Promoter is a fundamental DNA element located around the transcription start site (TSS) and
could regulate gene transcription. Promoter recognition is of great significance in …
could regulate gene transcription. Promoter recognition is of great significance in …
A comprehensive survey on genetic algorithms for DNA motif prediction
Computational DNA motif discovery is important because it allows for speedy and cost
effective analysis of sequences enriched with DNA motifs, performs large scale comparative …
effective analysis of sequences enriched with DNA motifs, performs large scale comparative …
DOOR: a prokaryotic operon database for genome analyses and functional inference
The rapid accumulation of fully sequenced prokaryotic genomes provides unprecedented
information for biological studies of bacterial and archaeal organisms in a systematic …
information for biological studies of bacterial and archaeal organisms in a systematic …
RSAT matrix-clustering: dynamic exploration and redundancy reduction of transcription factor binding motif collections
JA Castro-Mondragon, S Jaeger, D Thieffry… - Nucleic Acids …, 2017 - academic.oup.com
Transcription factor (TF) databases contain multitudes of binding motifs (TFBMs) from
various sources, from which non-redundant collections are derived by manual curation. The …
various sources, from which non-redundant collections are derived by manual curation. The …
Detecting N6-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines
As one of the most abundant RNA post-transcriptional modifications, N6-methyladenosine
(m6A) involves in a broad spectrum of biological and physiological processes ranging from …
(m6A) involves in a broad spectrum of biological and physiological processes ranging from …
iRNAD: a computational tool for identifying D modification sites in RNA sequence
Motivation Dihydrouridine (D) is a common RNA post-transcriptional modification found in
eukaryotes, bacteria and a few archaea. The modification can promote the conformational …
eukaryotes, bacteria and a few archaea. The modification can promote the conformational …
IRIS3: integrated cell-type-specific regulon inference server from single-cell RNA-Seq
A group of genes controlled as a unit, usually by the same repressor or activator gene, is
known as a regulon. The ability to identify active regulons within a specific cell type, ie, cell …
known as a regulon. The ability to identify active regulons within a specific cell type, ie, cell …
The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner
SS Antipov, MN Tutukina, EV Preobrazhenskaya… - PloS one, 2017 - journals.plos.org
Dps is a multifunctional homododecameric protein that oxidizes Fe2+ ions accumulating
them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing …
them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing …
Irna-m2g: identifying n2-methylguanosine sites based on sequence-derived information
RNA N 2-methylguanosine (m2G) is one kind of posttranscriptional modification and plays
crucial roles in the control and stabilization of tRNA. However, our knowledge about the …
crucial roles in the control and stabilization of tRNA. However, our knowledge about the …