Ki-67 protein has been widely used as a proliferation marker for human tumor cells for
decades. In recent studies, multiple molecular functions of this large protein have become …

Newer treatment strategy based on proliferative nuclear marker Ki-67 targeted therapy holds
promise for prioritized/personalized treatment options with regard to improved survival and …

Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely
used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 …

Background: The latest immunotherapy, used in the treatment of non-small cell lung cancer
(NSCLC), uses monoclonal antibodies directed against programmed death ligand 1 (PD-L1) …

What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in
histopathology? Discovered in 1983, the protein and its regulation of expression and …

The nuclear Ki‐67 protein (pKi‐67) has previously been shown to be exclusively expressed
in proliferating cells. As a result, antibodies against this protein are widely used as …

Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating
cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review …

When the nucleolus disassembles during open mitosis, many nucleolar proteins and RNAs
associate with chromosomes, establishing a perichromosomal compartment coating the …

Classification of lung neuroendocrine (NE) tumors is a step-wise process with four tumor
categories being identified by morphology, namely typical carcinoid (TC), atypical carcinoid …

It is estimated that 74,000 people in the United States and roughly 386,000 people globally
will be newly diagnosed with bladder cancer in 2015. 1, 2 Bladder cancer represents a …