[HTML][HTML] The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer

J Xu, J Xu, X Liu, J Jiang - Cell death discovery, 2022 - nature.com
Abstract Non-coding RNAs (ncRNAs), which occupy the vast majority of human transcripts
are known for their inability to encode proteins. NcRNAs consist of a diverse range of RNA …

[HTML][HTML] Long non-coding RNAs: from disease code to drug role

Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …

History, discovery, and classification of lncRNAs

J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

Mitochondrial mutations and mitoepigenetics: Focus on regulation of oxidative stress-induced responses in breast cancers

K Chen, P Lu, NM Beeraka, OA Sukocheva… - Seminars in cancer …, 2022 - Elsevier
Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-developing
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …

Potential of long non‐coding RNAs in cancer patients: from biomarkers to therapeutic targets

S Chandra Gupta… - International journal of …, 2017 - Wiley Online Library
Because of high specificity and easy detection in the tissues, serum, plasma, urine and
saliva, interest in exploring the potential of long non‐coding RNAs (lncRNAs) in cancer …

[HTML][HTML] Nuclear-mitochondrial interactions

BR Walker, CT Moraes - Biomolecules, 2022 - mdpi.com
Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Mitochondrial DNA: Epigenetics and environment

N Sharma, MS Pasala, A Prakash - Environmental and …, 2019 - Wiley Online Library
Maintenance of the mitochondrial genome is essential for proper cellular function. For this
purpose, mitochondrial DNA (mtDNA) needs to be faithfully replicated, transcribed …

[HTML][HTML] Emerging functions of mitochondria-encoded noncoding RNAs

B Ren, MX Guan, T Zhou, X Cai, G Shan - Trends in Genetics, 2023 - cell.com
Mitochondria, organelles that harbor their own circular genomes, are critical for energy
production and homeostasis maintenance in eukaryotic cells. Recent studies discovered …

Non‐coding RNAs: meet thy masters

FF Costa - Bioessays, 2010 - Wiley Online Library
New DNA sequencing technologies have provided novel insights into eukaryotic genomes,
epigenomes, and the transcriptome, including the identification of new non‐coding RNA …

Genetic aspects of mitochondrial genome evolution

M Bernt, A Braband, B Schierwater… - Molecular phylogenetics …, 2013 - Elsevier
Many years of extensive studies of metazoan mitochondrial genomes have established
differences in gene arrangements and genetic codes as valuable phylogenetic markers …