Parkinson disease

TA Zesiewicz - CONTINUUM: Lifelong Learning in Neurology, 2019 - journals.lww.com
PURPOSE OF REVIEW Parkinson disease is a common neurodegenerative disorder that
affects millions of people worldwide. Important advances in the treatment, etiology, and the …

[HTML][HTML] Depletion of dopamine in Parkinson's disease and relevant therapeutic options: A review of the literature

S Ramesh, ASPM Arachchige - AIMS neuroscience, 2023 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects motor and
cognition functions. The etiology of Parkinson's disease remains largely unknown, but …

GaborPDNet: Gabor transformation and deep neural network for Parkinson's disease detection using EEG signals

HW Loh, CP Ooi, E Palmer, PD Barua, S Dogan… - Electronics, 2021 - mdpi.com
Parkinson's disease (PD) is globally the most common neurodegenerative movement
disorder. It is characterized by a loss of dopaminergic neurons in the substantia nigra of the …

Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson's disease

AF Khan, Q Adewale, SJ Lin, TR Baumeister… - Nature …, 2023 - nature.com
Parkinson's disease involves multiple neurotransmitter systems beyond the classical
dopaminergic circuit, but their influence on structural and functional alterations is not well …

Automatic diagnosis of schizophrenia and attention deficit hyperactivity disorder in rs-fMRI modality using convolutional autoencoder model and interval type-2 fuzzy …

A Shoeibi, N Ghassemi, M Khodatars, P Moridian… - Cognitive …, 2023 - Springer
Nowadays, many people worldwide suffer from brain disorders, and their health is in danger.
So far, numerous methods have been proposed for the diagnosis of Schizophrenia (SZ) and …

Network degeneration in Parkinson's disease: multimodal imaging of nigro-striato-cortical dysfunction

MC Ruppert, A Greuel, M Tahmasian, F Schwartz… - Brain, 2020 - academic.oup.com
The spreading hypothesis of neurodegeneration assumes an expansion of neural
pathologies along existing neural pathways. Multimodal neuroimaging studies have …

Identification of exosomal biomarkers and its optimal isolation and detection method for the diagnosis of Parkinson's disease: A systematic review and meta-analysis

IS Nila, DM Sumsuzzman, ZA Khan, JH Jung… - Ageing research …, 2022 - Elsevier
Recently, there has been growing interest in exosomal biomarkers for their active targeting
and specificity for delivering their cargos (proteins, lipids, nucleic acids) from the parent cell …

A phase II study to evaluate the safety and efficacy of prasinezumab in early Parkinson's disease (PASADENA): rationale, design, and baseline data

G Pagano, FG Boess, KI Taylor, B Ricci… - Frontiers in …, 2021 - frontiersin.org
Background: Currently available treatments for Parkinson's disease (PD) do not slow clinical
progression nor target alpha-synuclein, a key protein associated with the disease. Objective …

Neuroimaging in dementia

AM Staffaroni, FM Elahi, D McDermott… - Seminars in …, 2017 - thieme-connect.com
Although the diagnosis of dementia still is primarily based on clinical criteria, neuroimaging
is playing an increasingly important role. This is in large part due to advances in techniques …

Parasympathetic autonomic dysfunction is more often evidenced than sympathetic autonomic dysfunction in fluctuating and polymorphic symptoms of" long-COVID" …

A Zanin, G Amah, S Chakroun, P Testard, A Faucher… - Scientific Reports, 2023 - nature.com
Several disabling symptoms potentially related to dysautonomia have been reported in “long-
COVID” patients. Unfortunately, these symptoms are often nonspecific, and autonomic …