Brain GABA levels across psychiatric disorders: A systematic literature review and meta‐analysis of 1H‐MRS studies

RR Schür, LWR Draisma, JP Wijnen… - Human brain …, 2016 - Wiley Online Library
The inhibitory gamma‐aminobutyric acid (GABA) system is involved in the etiology of most
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …

An update on the comorbidity of ADHD and ASD: A focus on clinical management

KM Antshel, Y Zhang-James, KE Wagner… - Expert review of …, 2016 - Taylor & Francis
Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD)
commonly co-occur. With the DSM-5, clinicians are permitted to make an ASD diagnosis in …

Comparative analyses of copy-number variation in autism spectrum disorder and schizophrenia reveal etiological overlap and biological insights

I Kushima, B Aleksic, M Nakatochi, T Shimamura… - Cell reports, 2018 - cell.com
Compelling evidence in Caucasian populations suggests a role for copy-number variations
(CNVs) in autism spectrum disorder (ASD) and schizophrenia (SCZ). We analyzed 1,108 …

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility

CB Klune, B Jin, LA DeNardo - Elife, 2021 - elifesciences.org
The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …

[HTML][HTML] Inhibitory control of the excitatory/inhibitory balance in psychiatric disorders

M Selten, H van Bokhoven, NN Kasri - F1000Research, 2018 - ncbi.nlm.nih.gov
Neuronal networks consist of different types of neurons that all play their own role in order to
maintain proper network function. The two main types of neurons segregate in excitatory and …

Neuron-glia interactions in neurodevelopmental disorders

YS Kim, J Choi, BE Yoon - Cells, 2020 - mdpi.com
Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder

SK Yadav, AA Bhat, S Hashem, S Nisar… - Translational …, 2021 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental
childhood-onset disorder characterized by a persistent pattern of inattentiveness …

[HTML][HTML] Brain imaging genetics in ADHD and beyond–Mapping pathways from gene to disorder at different levels of complexity

M Klein, M Onnink, M van Donkelaar, T Wolfers… - Neuroscience & …, 2017 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) is a common and often persistent
neurodevelopmental disorder. Beyond gene-finding, neurobiological parameters, such as …

Functional convergence of genomic and transcriptomic architecture underlies schooling behaviour in a live-bearing fish

A Corral-Lopez, NI Bloch, W van der Bijl… - Nature Ecology & …, 2024 - nature.com
The organization and coordination of fish schools provide a valuable model to investigate
the genetic architecture of affiliative behaviours and dissect the mechanisms underlying …

Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks

B Mossink, JR Van Rhijn, S Wang, K Linda… - Molecular …, 2022 - nature.com
Activity in the healthy brain relies on a concerted interplay of excitation (E) and inhibition (I)
via balanced synaptic communication between glutamatergic and GABAergic neurons. A …