Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

A review on nano-based drug delivery system for cancer chemoimmunotherapy

W Mu, Q Chu, Y Liu, N Zhang - Nano-Micro Letters, 2020 - Springer
Although notable progress has been made on novel cancer treatments, the overall survival
rate and therapeutic effects are still unsatisfactory for cancer patients …

Immune exosomes loading self-assembled nanomicelles traverse the blood–brain barrier for chemo-immunotherapy against glioblastoma

J Cui, X Wang, J Li, A Zhu, Y Du, W Zeng, Y Guo, L Di… - ACS …, 2023 - ACS Publications
Effective drug delivery and prevention of postoperative recurrence are significant challenges
for current glioblastoma (GBM) treatment. Poor drug delivery is mainly due to the presence …

Bacteria loaded with glucose polymer and photosensitive ICG silicon-nanoparticles for glioblastoma photothermal immunotherapy

R Sun, M Liu, J Lu, B Chu, Y Yang, B Song… - Nature …, 2022 - nature.com
Bacteria can bypass the blood-brain barrier (BBB), suggesting the possibility of employment
of bacteria for combating central nervous system diseases. Herein, we develop a bacteria …

Tumor–antigen activated dendritic cell membrane-coated biomimetic nanoparticles with orchestrating immune responses promote therapeutic efficacy against glioma

X Ma, L Kuang, Y Yin, L Tang, Y Zhang, Q Fan… - ACS …, 2023 - ACS Publications
Immunotherapy has had a profound positive effect on certain types of cancer but has not
improved the outcomes of glioma because of the blood–brain barrier (BBB) and …

Engineered nanoparticles for cancer vaccination and immunotherapy

ME Aikins, C Xu, JJ Moon - Accounts of chemical research, 2020 - ACS Publications
Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …

Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …

J Qi, S Jia, X Kang, X Wu, Y Hong, K Shan… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …

Glioma diagnosis and therapy: current challenges and nanomaterial-based solutions

T Li, J Li, Z Chen, S Zhang, S Li, S Wageh… - Journal of controlled …, 2022 - Elsevier
Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment

J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

Self‐amplified drug delivery with light‐inducible nanocargoes to enhance cancer immunotherapy

B Feng, B Hou, Z Xu, M Saeed, H Yu… - Advanced Materials, 2019 - Wiley Online Library
Chemoimmunotherapy by systemic administration of individual regimens suffers from
inconsistent pharmacokinetics profiles, low tumor specificity, and severe side effects …