APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease
RJ Jackson, MS Keiser, JC Meltzer, DP Fykstra… - Molecular Therapy, 2024 - cell.com
Epidemiological studies show that individuals who carry the relatively uncommon APOE ε2
allele rarely develop Alzheimer disease, and if they do, they have a later age of onset, milder …
allele rarely develop Alzheimer disease, and if they do, they have a later age of onset, milder …
Ependymal cells: roles in central nervous system infections and therapeutic application
S Xie, F Li - Journal of Neuroinflammation, 2024 - Springer
Ependymal cells are arranged along the inner surfaces of the ventricles and the central
canal of the spinal cord, providing anatomical, physiological and immunological barriers that …
canal of the spinal cord, providing anatomical, physiological and immunological barriers that …
Non-Invasive Gene Delivery to Brain Lymphatic System Using an Imaging Phased Array and Ultra-Short Focused Ultrasound Pulses
Neurodegenerative diseases such as Alzheimer's and Parkinson's are often characterized
by abnormal depositions of waste products, which often occur due to ineffective metabolite …
by abnormal depositions of waste products, which often occur due to ineffective metabolite …
Pulling the right viral levers: Engineering, screening and application of next-generation combinatorial AAV vectors
J Becker - 2023 - archiv.ub.uni-heidelberg.de
Adeno-associated viruses (AAVs) present powerful vectors for human gene therapy and
biomedical research. They enable the delivery of transgenes to a broad range of target …
biomedical research. They enable the delivery of transgenes to a broad range of target …
[PDF][PDF] Inaugural dissertation for obtaining the doctoral degree of the Combined Faculty of Mathematics, Engineering and Natural Sciences
MSNH Heber - scholar.archive.org
Adeno-associated viruses (AAVs) present powerful vectors for human gene therapy and
biomedical research. They enable the delivery of transgenes to a broad range of target …
biomedical research. They enable the delivery of transgenes to a broad range of target …