Lung cancer is the leading cause of global cancer incidence and mortality, accounting for an
estimated 2 million diagnoses and 1.8 million deaths. Neoplasms of the lungs are the …

The incidence and mortality from lung cancer is decreasing in the US due to decades of
public education and tobacco control policies, but are increasing elsewhere in the world …

To identify new susceptibility loci to lung cancer among diverse populations, we performed
cross-ancestry genome-wide association studies in European, East Asian and African …

Background Biological aging estimators derived from DNA methylation data are heritable
and correlate with morbidity and mortality. Consequently, identification of genetic and …

Lung cancer is the most frequent malignant neoplasm in most countries, and the main
cancer-related cause of mortality worldwide in both sexes combined. The geographic and …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Accurate colorectal cancer (CRC) risk prediction models are critical for identifying
individuals at low and high risk of developing CRC, as they can then be offered targeted …

Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …

Germ-line genetic control of gene expression occurs via expression quantitative trait loci
(eQTLs). We present a large, exon-specific eQTL data set covering ten human brain regions …

Background & Aims Guidelines for initiating colorectal cancer (CRC) screening are based
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …