Chemotherapeutic antibiotic doxorubicin belongs to the anthracycline class, slaughters not
only the cancer cells but also non-cancerous cells even in the non-targeted organs thereby …

Edible oils are the major natural dietary sources of tocopherols and tocotrienols, collectively
known as tocols. Plant foods with low lipid content usually have negligible quantities of …

DNA-damaging agents have a long history of use in cancer chemotherapy. The full extent of
their cellular mechanisms, which is essential to balance efficacy and toxicity, is often …

The anthracycline doxorubicin (DOX) is widely used in chemotherapy due to its efficacy in
fighting a wide range of cancers such as carcinomas, sarcomas and hematological cancers …

Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

The presented study was performed to verify whether rutin and/or quercetin can inhibit liver
injury induced by doxorubicin (DXR) in male Wistar rats. In this study, male Wistar rats were …

Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …

Legume seeds are rich sources of protein, fiber, and minerals. In addition, their phenolic
compounds as secondary metabolites render health benefits beyond basic nutrition …

Mature male Wistar rats (weighing 300–320g and each group six animals) were given
malathion (27mg/kg; 1/50 of the LD50 for an oral dose), vitamin C (200mg/kg)+ vitamin E …

The liver is the largest, important organ and the site for essential biochemical reactions in
the human body. It has the function to detoxify toxic substances and synthesize useful …