In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic
drugs are available on the market, and several compounds are in different phases of clinical …

This paper presents the results of stationary fluorescence spectroscopy and time-resolved
spectroscopy analyses of two 1, 3, 4-thiadiazole analogues, ie 4-(5-methyl-1, 3, 4-thiadiazol …

Abstract Potassium 8-R1-9-R2-10-R3-3-R-2-oxo-2H-[1, 2, 4] triazino [2, 3-c] quinazoline-6-
thiolates 2.1–2.26 were synthesized via cyclocondensation of 6-R-3-(3-R1-4-R2-5-R3 …

A new series of novel compounds 1-tert-butyl-9-substituted-12 H-indolo [2, 3-c] isoquinolino
[5, 6-c]-1, 2, 4-triazoles (4a–4c), 10-substituted-2-phenyl-1, 13-dihydroindolo [2, 3-c] …

The death rate from cancer and infectious diseases is still very high, therefore research in
this area is extremely important and promising as in medical, so in economic point of view …

The known methods for synthesis of thioxopyrimidines and their condensed analogs with
exocyclic sulfur atom are summarized and discussed. The most popular approaches are …

Introduction and Objective: The identification of a bioactive template (or lead) is one of the
important features of modern drug discovery. Natural products, synthetic and …

Алкілування калій 9-R<^> 1-10-R<^> 2-3-R-2-оксо-2Н-[1, 2, 4] триазино [2, 3-с] хіназолін-
6-тіолатів N-циклоалкіл-(циклоалкіларил-)-2-хлорацетамідами та взаємодія …

A simple and effective method has been developed for the synthesis of previously unknown
substituted 3-R 1-6-R 3-6, 7-dihydro-2 H-[1, 2, 4] triazino-[2, 3-c] quinazolin-2-ones by …