As the importance of cell heterogeneity has begun to be emphasized, single-cell
sequencing approaches are rapidly adopted to study cell heterogeneity and cellular …

The journey of a hematopoietic stem cell (HSC) involves the passage through successive
anatomical sites where HSCs are in direct contact with their surrounding microenvironment …

In vitro generation and expansion of hematopoietic stem cells (HSCs) holds great promise
for the treatment of any ailment that relies on bone marrow or blood transplantation. To …

Intercellular communication orchestrates a multitude of physiologic and pathologic
conditions. Algorithms to infer cell–cell communication and predict downstream signalling …

It is increasingly recognized that specialized subsets of endothelial cells carry out unique
functions in specific organs and regions of the vascular tree. Perhaps the most striking …

Haematopoietic stem and progenitor cells emerge from specialized haemogenic endothelial
cells in select vascular beds during embryonic development. Specification and commitment …

Hematopoietic stem cells (HSCs), the apex of the hierarchically organized blood cell
production system, are generated in the yolk sac, aorta-gonad-mesonephros region and …

Live cell imaging uniquely enables the measurement of dynamic events in single cells, but it
has not been used often in the study of gene regulatory networks. Network components can …