Huntington's disease therapeutic compounds

BL Davidson, AM Monteys - US Patent 9,523,093, 2016 - Google Patents
4,962,091 A 10/1990 Eppstein et al. 5,139,941 A 8/1992 Muzyczka et al. 5,173,414 A
12/1992 Lebkowski et al. 5,350,674. A 9, 1994 Boenisch et al. 5,585,362 A 12/1996 Wilson …

Therapeutic compounds

BL Davidson, RL Boudreau - US Patent 9,181,544, 2015 - Google Patents
US9181544B2 - Therapeutic compounds - Google Patents US9181544B2 - Therapeutic
compounds - Google Patents Therapeutic compounds Download PDF Info Publication number …

Structurally designed shRNAs

GJ Hannon, S Cheloufi - US Patent 8,993,532, 2015 - Google Patents
2008, 0213861 A1 9, 2008 Hannon et al. 2008/0293142 A1* 11/2008 Liu et al........................
435/455 2009, 0004668 A1 1/2009 Chen et al. 2009, O124566 A1 5, 2009 Chi et al …

RNA interference suppression of neurodegenerative diseases and methods of use thereof

BL Davidson, H Xia, Q Mao, H Paulson… - US Patent …, 2016 - Google Patents
US9260716B2 - RNA interference suppression of neurodegenerative diseases and
methods of use thereof - Google Patents US9260716B2 - RNA interference suppression of …

siRNA-mediated gene silencing

BL Davidson, H Paulson, V Miller, C Gouvion - US Patent 9,487,779, 2016 - Google Patents
US9487779B2 - siRNA-mediated gene silencing - Google Patents US9487779B2 - siRNA-mediated
gene silencing - Google Patents siRNA-mediated gene silencing Download PDF Info Publication …

SiRNA-mediated gene silencing

BL Davidson, H Paulson, V Miller, C Gouvion - US Patent 8,779,116, 2014 - Google Patents
US8779116B2 - SiRNA-mediated gene silencing - Google Patents US8779116B2 - SiRNA-mediated
gene silencing - Google Patents SiRNA-mediated gene silencing Download PDF Info Publication …

Identification of micro-RNAS involved in neuromuscular synapse maintenance and regeneration

A Williams, E Olson - US Patent 8,202,848, 2012 - Google Patents
5,994,315 A 1 1/1999 Nyce et al. 6,025,339 A 2/2000 Nyce 6,040,296 A 3/2000 Nyce 6.825,
174 B2 11/2004 Nyce 7,034,007 B1 4/2006 Nyce et al. 7,229,774 B2 6/2007 Chinnaiyan et …

Alternative export pathways for vector expressed RNA interference

S Harper, BL Davidson - US Patent 10,006,028, 2018 - Google Patents
US10006028B2 - Alternative export pathways for vector expressed RNA interference - Google
Patents US10006028B2 - Alternative export pathways for vector expressed RNA interference …

Reduction of off-target RNA interference toxicity

BL Davidson, AM Monteys, JL McBride… - US Patent …, 2017 - Google Patents
2013-09-03 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …

Novel sirna structure for minimizing off-target effects and relaxing saturation of rnai machinery and the use thereof

DK Lee, CI Chang - US Patent App. 12/808,772, 2012 - Google Patents
The present invention relates to a novel siRNA structure and the use thereof. More
particularly, the invention relates to a double-stranded small interfering RNA molecule …