Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future

G Ménard, A Rouillon, V Cattoir… - Frontiers in cellular and …, 2021 - frontiersin.org
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …

Galleria mellonella as a consolidated in vivo model hosts: New developments in antibacterial strategies and novel drug testing

MA Cutuli, G Petronio Petronio, F Vergalito, I Magnifico… - Virulence, 2019 - Taylor & Francis
ABSTRACT A greater ethical conscience, new global rules and a modified perception of
ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo …

The greater wax moth Galleria mellonella: biology and use in immune studies

I Wojda, B Staniec, M Sułek… - Pathogens and …, 2020 - academic.oup.com
The greater wax moth Galleria mellonella is an invertebrate that is increasingly being used
in scientific research. Its ease of reproduction, numerous offspring, short development cycle …

Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens

TC Pereira, PP De Barros, LRO Fugisaki, RD Rossoni… - Journal of Fungi, 2018 - mdpi.com
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile

L Scorzoni, MP de Lucas, AC Mesa-Arango… - PloS one, 2013 - journals.plos.org
The incidence of opportunistic fungal infections has increased in recent decades due to the
growing proportion of immunocompromised patients in our society. Candida krusei has …

Our current clinical understanding of Candida biofilms: where are we two decades on?

G Ramage, E Borghi, CF Rodrigues, R Kean… - APMIS, 2023 - Wiley Online Library
Clinically we have been aware of the concept of Candida biofilms for many decades, though
perhaps without the formal designation. Just over 20 years ago the subject emerged on the …

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications

A Forastiero, AC Mesa-Arango… - Antimicrobial Agents …, 2013 - Am Soc Microbiol
Candida tropicalis ranks between third and fourth among Candida species most commonly
isolated from clinical specimens. Invasive candidiasis and candidemia are treated with …

[HTML][HTML] Invertebrate models of fungal infection

M Arvanitis, J Glavis-Bloom, E Mylonakis - Biochimica et Biophysica Acta …, 2013 - Elsevier
The morbidity, mortality and economic burden associated with fungal infections, together
with the emergence of fungal strains resistant to current antimicrobial agents, necessitate …

Unexplored endemic fruit species from Brazil: Antibiofilm properties, insights into mode of action, and systemic toxicity of four Eugenia spp.

JCO Sardi, IA Freires, JG Lazarini, J Infante… - Microbial …, 2017 - Elsevier
Brazilian endemic fruit species have aroused attention due to their highly valuable, yet
unexplored, agro-industrial, food and therapeutic potential. Herein, we describe the …

Searching new antifungals: The use of in vitro and in vivo methods for evaluation of natural compounds

L Scorzoni, F Sangalli-Leite… - Journal of …, 2016 - Elsevier
In the last decades, the increased number of immunocompromised patients has led to the
emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of …