Hyperthermia treatment as a promising anti-cancer strategy: therapeutic targets, perspective mechanisms and synergistic combinations in experimental approaches
GY Yi, MJ Kim, HI Kim, J Park, SH Baek - Antioxidants, 2022 - mdpi.com
Despite recent developments in diagnosis and treatment options, cancer remains one of the
most critical threats to health. Several anti-cancer therapies have been identified, but further …
most critical threats to health. Several anti-cancer therapies have been identified, but further …
Modulated electro-hyperthermia-induced tumor damage mechanisms revealed in cancer models
T Krenacs, N Meggyeshazi, G Forika, E Kiss… - International journal of …, 2020 - mdpi.com
The benefits of high-fever range hyperthermia have been utilized in medicine from the
Ancient Greek culture to the present day. Amplitude-modulated electro-hyperthermia …
Ancient Greek culture to the present day. Amplitude-modulated electro-hyperthermia …
Heat shock factor 1 inhibition enhances the effects of modulated electro hyperthermia in a triple negative breast cancer mouse model
PHL Viana, CA Schvarcz, LO Danics, B Besztercei… - Scientific Reports, 2024 - nature.com
Female breast cancer is the most diagnosed cancer worldwide. Triple negative breast
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
[HTML][HTML] Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer
P Viana, P Hamar - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Abstract The Heat Shock Response (HSR) is a cellular stress reaction crucial for cell survival
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
Lucidone inhibits autophagy and MDR1 via HMGB1/RAGE/PI3K/Akt signaling pathway in pancreatic cancer cells
SY Chen, YH Hsu, SY Wang, YY Chen… - Phytotherapy …, 2022 - Wiley Online Library
Gemcitabine (GEM) drug resistance remains a difficult challenge in pancreatic ductal
adenocarcinoma (PDAC) treatment. Therefore, identifying a safe and effective treatment …
adenocarcinoma (PDAC) treatment. Therefore, identifying a safe and effective treatment …
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology
P Wust, U Stein, P Ghadjar - International Journal of Hyperthermia, 2021 - Taylor & Francis
The temperature-independent effects of electromagnetic fields (EMF) have been
controversial for decades. Here, we critically analyze the available literature on non-thermal …
controversial for decades. Here, we critically analyze the available literature on non-thermal …
Tumor suppressor protein p53 and inhibitor of apoptosis proteins in colorectal cancer—A promising signaling network for therapeutic interventions
Ö Güllülü, S Hehlgans, C Rödel, E Fokas, F Rödel - Cancers, 2021 - mdpi.com
Simple Summary Tumor suppressor 53 (p53) is a multifunctional protein that regulates cell
cycle, DNA repair, apoptosis and metabolic pathways. In colorectal cancer (CRC), mutations …
cycle, DNA repair, apoptosis and metabolic pathways. In colorectal cancer (CRC), mutations …
The iron chelator desferrioxamine synergizes with chemotherapy for cancer treatment
L Wang, X Li, Y Mu, C Lu, S Tang, K Lu, X Qiu… - Journal of Trace …, 2019 - Elsevier
Background Cisplatin (CDDP) resistance remains a major obstacle for treatment of ovarian
cancer. Iron contributes to the growth and reproduction of malignant cells, thus iron chalators …
cancer. Iron contributes to the growth and reproduction of malignant cells, thus iron chalators …
Review of the clinical evidences of modulated electro-hyperthermia (mEHT) method: an update for the practicing oncologist
AM Szasz, CA Minnaar, G Szentmártoni… - Frontiers in …, 2019 - frontiersin.org
Background: Modulated electro-hyperthermia (mEHT) is a variation of the conventional
hyperthermia which selectively targets the malignant cell membranes in order to heat the …
hyperthermia which selectively targets the malignant cell membranes in order to heat the …
Exhaustion of protective heat shock response induces significant tumor damage by apoptosis after modulated electro-hyperthermia treatment of triple negative breast …
L Danics, CA Schvarcz, P Viana, T Vancsik, T Krenács… - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer is one of the most frequent cancer types among women
worldwide. Triple-negative breast cancer is a highly aggressive breast cancer type with very …
worldwide. Triple-negative breast cancer is a highly aggressive breast cancer type with very …