Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

This guideline update reflects substantial advances in the epidemiology, determinants,
pathophysiology, assessment, prevention and treatment of obesity, and shifts the focus of …

Over the past decade, great progress has been made in understanding the complexity of
adipose tissue biology and its role in metabolism. This includes new insights into the …

Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes.
The exact mechanism by which adipose tissue induces insulin resistance is still unclear. It …

More than one-third of the worldwide population is overweight or obese and therefore at risk
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …

The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …

Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Obesity is an epidemic disease characterized by chronic low-grade inflammation associated
with a dysfunctional fat mass. Adipose tissue is now considered an extremely active …