In comparison with the pervasive use of protein dimers and multimers in all domains of life,
functional RNA oligomers have so far rarely been observed in nature. Their diminished …

The T‐box riboswitches are widespread bacterial noncoding RNAs that directly bind specific
tRNAs, sense aminoacylation on bound tRNAs, and switch conformations to control amino …

T-box riboswitches are multi-domain noncoding RNAs that surveil individual amino acid
availabilities in most Gram-positive bacteria. T-boxes directly bind specific tRNAs, query …

T-box riboswitches are unique riboregulators where gene regulation is mediated through
interactions between two highly structured RNAs. Despite extensive structural insights, how …

Amino acid availability in Gram-positive bacteria is monitored by T-box riboswitches. T-
boxes directly bind tRNAs, assess their aminoacylation state, and regulate the transcription …

T-box riboswitches are noncoding RNA elements involved in genetic regulation of most
Gram-positive bacteria. They regulate amino acid metabolism by assessing the …

When the primitive translation system first emerged in the hypothetical RNA world,
ribozymes could have been responsible for aminoacylation. Given that naturally occurring T …

T-box riboswitches are modular bacterial noncoding RNAs that sense and regulate amino
acid availability through direct interactions with tRNAs. Between the 5′ anticodon-binding …

Complex RNA–RNA interactions are increasingly known to play key roles in numerous
biological processes from gene expression control to ribonucleoprotein granule formation …

In Staphylococcus aureus, de novo methionine biosynthesis is regulated by a unique
hierarchical pathway involving stringent-response controlled CodY repression in …