Oligodendrocytes are glial cells that populate the entire CNS after they have differentiated
from oligodendrocyte progenitor cells. From birth onward, oligodendrocytes initiate wrapping …

The myelination of axons by oligodendrocytes is a highly complex cell-to-cell interaction.
Oligodendrocytes and axons have a reciprocal signaling relationship in which …

Investigating human oligodendrogenesis and the interaction of oligodendrocytes with
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …

Multiple Sclerosis (MS) is a major cause of neurological disability, which increases
predominantly during disease progression as a result of cortical and grey matter structures …

The myelination of axons has evolved to enable fast and efficient transduction of electrical
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …

Over the past several decades a large amount of data have established that glial cells, the
main cell population in the brain, dynamically interact with neurons and thus impact their …

Astrocytes are known to play critical roles in central nervous system development,
homeostasis, and response to injury. In addition to well-defined functions in synaptic …

Background In the central nervous system (CNS), connexin 43 (Cx43) is mainly expressed
in astrocytes and regulates astrocytic network homeostasis. Similar to Cx43 overexpression …

In the central nervous system (CNS), connexin (Cx) s and pannexin (Panx) s are an integral
component of homeostatic neuronal excitability and synaptic plasticity. Neuronal Cx gap …