Introduction Pyrimidine nucleotides are essential for the parasite's growth and replication.
Parasites have only a de novo pathway for the biosynthesis of pyrimidine nucleotides …

Cancer, the most significant cause of morbidity and mortality, has already posed a heavy
burden on health care systems globally. In recent years, cancer treatment has made a …

The nanoscale multidrug codelivery system for synergistic therapy is an effective strategy for
tumor treatment. However, the low drug delivery efficiency and poor therapeutic effects limit …

Malaria is one of our planet's most widespread and deadliest diseases, and there is an ever-
consistent need for new and improved pharmaceuticals. Natural products have been an …

Visible‐light‐induced photoreaction of carboranes is an effective approach to prepare
carborane‐containing compounds. While several methods involving boron‐centered …

Prodrug self-delivery carriers with targeting that specifically responded to tumor
microenvironments have good potential to improve the application dilemma of approved …

Artemisinin (ART) and its derivatives have great therapeutical utility as antimalarials and can
be repurposed for other indications, such as viral infections, autoimmune diseases, and …

Ferroptosis, as a way of cell death, participates in the body's normal physiological and
pathological regulation. Recent studies have shown that ferroptosis may damage glucose …

Glycoconjugates are biologically significant molecules as they tend to serve a wide range of
intra-and extra-cellular processes depending on their size and complexity. The secondary …

Organic peroxides are an important class of compounds for organic synthesis,
pharmacological chemistry, materials science, and the polymer industry. Here, for the first …