Modern approaches for evaluating treatment effect heterogeneity from clinical trials and observational data

I Lipkovich, D Svensson, B Ratitch… - Statistics in …, 2024 - Wiley Online Library
In this paper, we review recent advances in statistical methods for the evaluation of the
heterogeneity of treatment effects (HTE), including subgroup identification and estimation of …

Learning optimal group-structured individualized treatment rules with many treatments

H Ma, D Zeng, Y Liu - Journal of Machine Learning Research, 2023 - jmlr.org
Data driven individualized decision making problems have received a lot of attentions in
recent years. In particular, decision makers aim to determine the optimal Individualized …

Learning optimal distributionally robust individualized treatment rules

W Mo, Z Qi, Y Liu - Journal of the American Statistical Association, 2021 - Taylor & Francis
Recent development in the data-driven decision science has seen great advances in
individualized decision making. Given data with individual covariates, treatment …

A semiparametric instrumental variable approach to optimal treatment regimes under endogeneity

Y Cui, E Tchetgen Tchetgen - Journal of the American Statistical …, 2021 - Taylor & Francis
There is a fast-growing literature on estimating optimal treatment regimes based on
randomized trials or observational studies under a key identifying condition of no …

Learning individualized treatment rules with many treatments: A supervised clustering approach using adaptive fusion

H Ma, D Zeng, Y Liu - Advances in Neural Information …, 2022 - proceedings.neurips.cc
Abstract Learning an optimal Individualized Treatment Rule (ITR) is a very important
problem in precision medicine. This paper is concerned with the challenge when the …

Optimizing pessimism in dynamic treatment regimes: A bayesian learning approach

Y Zhou, Z Qi, C Shi, L Li - International Conference on …, 2023 - proceedings.mlr.press
In this article, we propose a novel pessimism-based Bayesian learning method for optimal
dynamic treatment regimes in the offline setting. When the coverage condition does not hold …

Rate-optimal contextual online matching bandit

Y Li, C Wang, G Cheng, WW Sun - arXiv preprint arXiv:2205.03699, 2022 - arxiv.org
Two-sided online matching platforms have been employed in various markets. However,
agents' preferences in present market are usually implicit and unknown and must be learned …

Off-policy evaluation in doubly inhomogeneous environments

Z Bian, C Shi, Z Qi, L Wang - Journal of the American Statistical …, 2024 - Taylor & Francis
This work aims to study off-policy evaluation (OPE) under scenarios where two key
reinforcement learning (RL) assumptions—temporal stationarity and individual homogeneity …

Estimation and validation of ratio-based conditional average treatment effects using observational data

S Yadlowsky, F Pellegrini, F Lionetto… - Journal of the …, 2021 - Taylor & Francis
While sample sizes in randomized clinical trials are large enough to estimate the average
treatment effect well, they are often insufficient for estimation of treatment-covariate …

Efficient learning of optimal individualized treatment rules for heteroscedastic or misspecified treatment-free effect models

W Mo, Y Liu - Journal of the Royal Statistical Society Series B …, 2022 - academic.oup.com
Recent development in data-driven decision science has seen great advances in
individualized decision making. Given data with individual covariates, treatment …