M1/M2 macrophage-targeted nanotechnology and PROTAC for the treatment of atherosclerosis
Y Ma, X Yang, K Ning, H Guo - Life Sciences, 2024 - Elsevier
Macrophages play key roles in atherosclerosis progression, and an imbalance in M1/M2
macrophages leads to unstable plaques; therefore, M1/M2 macrophage polarization …
macrophages leads to unstable plaques; therefore, M1/M2 macrophage polarization …
Biomembrane camouflaged nanoparticles: a paradigm shifts in targeted drug delivery system
SA Qureshi, K Rafiya, S Awasthi, A Jain, A Nadaf… - Colloids and Surfaces B …, 2024 - Elsevier
Targeted drug delivery has emerged as a pivotal approach within precision medicine,
aiming to optimize therapeutic efficacy while minimizing systemic side effects. Advanced …
aiming to optimize therapeutic efficacy while minimizing systemic side effects. Advanced …
[HTML][HTML] An anti-inflammatory Glyburide-loaded nanoghost for atherosclerosis therapy: A red blood cell based bio-mimetic strategy
Z Karami, M Akrami, J Mehrzad, M Esfandyari-Manesh… - Giant, 2023 - Elsevier
Inflammation control is becoming a critical strategy for atherosclerosis management,
because inflammation is involved in plaque progression. In this regard, a biomimetic …
because inflammation is involved in plaque progression. In this regard, a biomimetic …
Recent progress in biomimetic nanomedicines based on versatile targeting strategy for atherosclerosis therapy
L Liang, Y Deng, Z Ao, C Liao, J Tian, C Li… - Journal of Drug …, 2024 - Taylor & Francis
Atherosclerosis (AS) is considered to be one of the major causes of cardiovascular disease.
Its pathological microenvironment is characterised by increased production of reactive …
Its pathological microenvironment is characterised by increased production of reactive …
[HTML][HTML] Nanoparticle-Based Immunotherapy for Reversing T-Cell Exhaustion
F Li, Y Wang, D Chen, Y Du - International Journal of Molecular Sciences, 2024 - mdpi.com
T-cell exhaustion refers to a state of T-cell dysfunction commonly observed in chronic
infections and cancer. Immune checkpoint molecules blockading using PD-1 and TIM-3 …
infections and cancer. Immune checkpoint molecules blockading using PD-1 and TIM-3 …
[HTML][HTML] Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support …
A Krishnan, DG Callanan, VG Sendra, A Lad… - Pharmaceuticals, 2024 - mdpi.com
An inflammation-resolving polysialic acid-decorated PLGA nanoparticle (PolySia-NP) has
been developed to treat geographic atrophy/age-related macular degeneration and other …
been developed to treat geographic atrophy/age-related macular degeneration and other …
[HTML][HTML] Biomaterials for treating sepsis-induced thromboinflammation
Sepsis is a common and life-threatening disorder with an alarmingly high mortality rate.
Unfortunately, this rate has not decreased significantly over the last decade and the number …
Unfortunately, this rate has not decreased significantly over the last decade and the number …
[HTML][HTML] Extraction, Isolation, and Component Analysis of Turmeric-Derived Exosome-like Nanoparticles
Y Wei, X Cai, Q Wu, H Liao, S Liang, H Fu, Q Xiang… - Bioengineering, 2023 - mdpi.com
As one kind of plant-derived extracellular vesicle, turmeric-derived exosome-like
nanoparticles (TELNs) are composed of proteins, lipids, nucleic acids, and small-molecule …
nanoparticles (TELNs) are composed of proteins, lipids, nucleic acids, and small-molecule …