[HTML][HTML] Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Conquering the hypoxia limitation for photodynamic therapy

Y Wan, LH Fu, C Li, J Lin, P Huang - Advanced Materials, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …

High-performance self-cascade pyrite nanozymes for apoptosis–ferroptosis synergistic tumor therapy

X Meng, D Li, L Chen, H He, Q Wang, C Hong, J He… - ACS …, 2021 - ACS Publications
As next-generation artificial enzymes, nanozymes have shown great promise for tumor
catalytic therapy. In particular, their peroxidase-like activity has been employed to catalyze …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Mesoporous silica nanoparticles for drug delivery

M Manzano, M ValletRegí - Advanced functional materials, 2020 - Wiley Online Library
In recent years, nanomedicine has emerged at the forefront of nanotechnology, generating
great expectations in the biomedical field. Researchers are developing novel nanoparticles …

[HTML][HTML] Bromelain a potential bioactive compound: a comprehensive overview from a pharmacological perspective

AJ Chakraborty, S Mitra, TE Tallei, AM Tareq, F Nainu… - Life, 2021 - mdpi.com
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

Cell membrane coated semiconducting polymer nanoparticles for enhanced multimodal cancer phototheranostics

J Li, X Zhen, Y Lyu, Y Jiang, J Huang, K Pu - Acs Nano, 2018 - ACS Publications
Phototheranostic nanoagents are promising for early diagnosis and precision therapy of
cancer. However, their imaging ability and therapeutic efficacy are often limited due to the …

[HTML][HTML] The role of tumor microenvironment in chemoresistance: to survive, keep your enemies closer

DA Senthebane, A Rowe, NE Thomford… - International journal of …, 2017 - mdpi.com
Chemoresistance is a leading cause of morbidity and mortality in cancer and it continues to
be a challenge in cancer treatment. Chemoresistance is influenced by genetic and …