Therapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of
complex diseases, especially for conditions that lack efficacious treatment. The successful …

Translation of the mRNA-encoded genetic information into proteins is catalyzed by the
intricate ribonucleoprotein machine, the ribosome. Historically, the bacterial ribosome is …

Protein synthesis by the ribosome is highly dependent on the ionic conditions in the cellular
environment, but the roles of ribosome solvation have remained poorly understood …

Native mass spectrometry (MS) is a rapidly advancing field in the analysis of proteins,
protein complexes, and macromolecular species of various types. The majority of native MS …

N-terminal acetylation (NTA) is one of the most abundant protein modifications known, and
the N-terminal acetyltransferase (NAT) machinery is conserved throughout all Eukarya. Over …

Ribosomal proteins (RPs) are indispensable in ribosome biogenesis and protein synthesis,
and play a crucial role in diverse developmental processes. Our previous studies on …

Rice cultivation by transplanting requires plenty of water. It might become a challenging task
in future to grow rice by transplanting due to the climatic change, water and labor scarcities …

Ribosomes consist of many small proteins and few large RNA molecules. Both components
are necessary for ribosome functioning during translation. According to widely accepted …

Bacterial ribosomal protein S1 is the largest and highly flexible protein of the 30S subunit,
and one of a few core ribosomal proteins for which a complete structure is lacking. S1 is …

In vitro reconstitution is a powerful tool for investigating ribosome functions and biogenesis,
as well as discovering new ribosomal features. In this study, we integrated all of the …