Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

MA La Merrill, LN Vandenberg, MT Smith… - Nature Reviews …, 2020 - nature.com
Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with
hormone action, thereby increasing the risk of adverse health outcomes, including cancer …

Update on the health effects of bisphenol A: overwhelming evidence of harm

FS Vom Saal, LN Vandenberg - Endocrinology, 2021 - academic.oup.com
In 1997, the first in vivo bisphenol A (BPA) study by endocrinologists reported that feeding
BPA to pregnant mice induced adverse reproductive effects in male offspring at the low dose …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Bisphenol A and human health: a review of the literature

JR Rochester - Reproductive toxicology, 2013 - Elsevier
There is growing evidence that bisphenol A (BPA) may adversely affect humans. BPA is an
endocrine disruptor that has been shown to be harmful in laboratory animal studies. Until …

A review of the carcinogenic potential of bisphenol A

DD Seachrist, KW Bonk, SM Ho, GS Prins… - Reproductive …, 2016 - Elsevier
The estrogenic properties of bisphenol A (BPA), a ubiquitous synthetic monomer that can
leach into the food and water supply, have prompted considerable research into exposure …

Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations

M Manikkam, R Tracey, C Guerrero-Bosagna… - PloS one, 2013 - journals.plos.org
Environmental compounds are known to promote epigenetic transgenerational inheritance
of adult onset disease in subsequent generations (F1–F3) following ancestral exposure …

State of the evidence 2017: an update on the connection between breast cancer and the environment

JM Gray, S Rasanayagam, C Engel, J Rizzo - Environmental Health, 2017 - Springer
Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …

Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects

BS Rubin - The Journal of steroid biochemistry and molecular …, 2011 - Elsevier
Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. This
compound is a building block of polycarbonate plastics often used for food and beverage …

Endocrine disrupting chemicals and disease susceptibility

TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …

Non-monotonic dose-response relationships and endocrine disruptors: a qualitative method of assessment

F Lagarde, C Beausoleil, SM Belcher… - Environmental …, 2015 - Springer
Experimental studies investigating the effects of endocrine disruptors frequently identify
potential unconventional dose-response relationships called non-monotonic dose-response …