Advances in biomaterials and the need for patient-specific bone scaffolds require modern
manufacturing approaches in addition to a design strategy. Hybrid materials such as those …

Bioprinting is rapidly being adopted as a major method for fabricating tissue engineering
constructs. Through the precise deposition of cell-and bioactive molecule-laden materials …

High-strength fully porous biomaterials built with additive manufacturing provide an exciting
opportunity for load-bearing orthopedic applications. While factors controlling their …

Topology optimization is the process of determining the optimal layout of material and
connectivity inside a design domain. This paper surveys topology optimization of continuum …

With the increasing application of orthopedic scaffolds, a dramatically increasing number of
requirements for scaffolds are precise. The porous structure has been a fundamental design …

A review about design, manufacture, and mechanobiology of biodegradable scaffolds for
bone tissue engineering is given. First, fundamental aspects about bone tissue engineering …

Purpose This paper aims to provide a comprehensive review of the state-of–the-art design
methods for additive manufacturing (AM) technologies to improve functional performance …

Porous design of orthopaedic implants affords the advantages of minimizing stress shielding
and improving the osseointegration and long-term stability. However, the marked error in the …

Tissue scaffolds provide structural support while facilitating tissue growth, but are
challenging to design due to diverse property trade-offs. Here, a computational approach …

The design and fabrication of tissue engineering scaffolds is a highly complex process. In
order to provide a proper architecture for cells to grow, proliferate, and differentiate to form …