Introduction While magnetic resonance imaging (MRI) is established in diagnosing and
monitoring disease activity in multiple sclerosis (MS), its utility in predicting and monitoring …

T1/T2-weighted ratio is a novel magnetic resonance imaging (MRI) biomarker based on
conventional sequences, related to microstructural integrity and with increasing use in …

Background: In multiple sclerosis (MS), iron rim lesions (IRLs) are associated with
pronounced tissue damage, higher disease severity and have been suggested as an …

Purpose Studies at 3T have shown that T1 relaxometry enables characterization of brain
tissues at the single‐subject level by comparing individual physical properties to a normative …

Abstract Purpose T1 Magnetization Prepared Two Rapid Acquisition Gradient Echo
(MP2RAGE) with compress sensing (CS) has been proposed as an improvement of the …

BACKGROUND AND PURPOSE: MS lesions exhibit varying degrees of axonal and myelin
damage. A comprehensive description of lesion phenotypes could contribute to an improved …

Methods We analysed T1 and T2 relaxometry maps from a longitudinal cohort of MS
patients. Lesions were classified as enlarging, shrinking, new or stable based on their …

Objectives Microstructural characterization of patients with multiple sclerosis (MS) has been
shown to correlate better with disability compared to conventional radiological biomarkers …

Multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD) and myelin
oligodendrocyte glycoprotein antibody associated disease (MOGAD) are inflammatory …

Brain imaging plays a pivotal role in the clinical management of demyelinating diseases
affecting the central nervous system (CNS). Conventional MR imaging is essential for …